Evaluation of Platelet-Rich Plasma Versus Topical Minoxidil (5%) in Combination with Oral Finasteride for the Treatment of Androgenic Alopecia

August 2024 in “ Pakistan Journal of Health Sciences ”

Muhammad Erfan, Sumyra Saleem, Ashraf Hussain, Masud Rana, Sameer Ahmed, Amanat Ali

platelet-rich plasma PRP topical minoxidil minoxidil oral finasteride finasteride androgenic alopecia hair density hair regrowth Rogaine Propecia

TLDR PRP with finasteride is better for hair regrowth than minoxidil with finasteride.

This study compared the efficacy of platelet-rich plasma (PRP) and topical minoxidil (5%) when used alongside oral finasteride for treating androgenic alopecia. Conducted from March to August 2023, it involved 80 patients aged 18 to 65, divided into two groups: Group A received monthly PRP injections and daily oral finasteride, while Group B used topical minoxidil twice daily and daily oral finasteride. Results showed that Group A had a significantly higher mean hair density (101.6 ± 11.2 hair/cm²) compared to Group B (87.0 ± 9.0 hair/cm², p < 0.001). The study concluded that PRP combined with oral finasteride is more effective in improving hair regrowth, density, and patient satisfaction than the combination of topical minoxidil and oral finasteride.

View this study on thejas.com.pk →

Discuss this study in the Community →

Cited in this study

16 / 16 results

research Factors Associated With Early-Onset Androgenetic Alopecia: A Scoping Review

March 2024 in “PLOS ONE”

Early-onset baldness is linked to genetics, lifestyle, and can indicate higher risk for heart and metabolic diseases, and affects mental health.

Comparison of Efficacy of Platelet-Rich Plasma With and Without Topical Minoxidil for Hair Growth in Patients With Androgenetic Alopecia: A Prospective Study

research Comparison of Efficacy of Platelet-Rich Plasma With and Without Topical Minoxidil for Hair Growth in Patients With Androgenetic Alopecia: A Prospective Study

February 2024 in “Cureus”

PRP therapy with minoxidil is more effective for hair growth than PRP alone.

research Efficacy of Platelet-Rich Plasma Versus 5% Topical Minoxidil for the Treatment of Androgenetic Alopecia

January 2024 in “JCPSP. Journal of the College of Physicians & Surgeons Pakistan”

PRP therapy is more effective than minoxidil for treating hair loss from androgenetic alopecia.

Evaluation of Platelet-Rich Plasma Plus Basic Fibroblast Growth Factor Combined With Minoxidil in the Treatment of Androgenetic Alopecia: A Randomized Controlled Trial

research Evaluation of Platelet-Rich Plasma Plus Basic Fibroblast Growth Factor Combined With Minoxidil in the Treatment of Androgenetic Alopecia: A Randomized Controlled Trial

May 2023 in “Journal of Cosmetic Dermatology”

Using platelet-rich plasma, basic fibroblast growth factor, and minoxidil together significantly increases hair count and growth rate in people with hair loss.

research What's New in Therapy for Male Androgenetic Alopecia?

2 citations, September 2022 in “American Journal of Clinical Dermatology”

research Comorbidities in Androgenetic Alopecia: A Comprehensive Review

September 2022 in “Dermatology and therapy”

Androgenetic alopecia is linked to heart disease, metabolic issues, and mental health problems.

research Epidemiology and Disease Burden of Androgenetic Alopecia in College Freshmen in China: A Population-Based Study

1 citations, February 2022 in “PLOS ONE”

Hair loss is more common in male Chinese college freshmen, and it's linked with rosacea but doesn't affect their quality of life.

research Combination Therapy with Platelet-Rich Plasma and Minoxidil Leads to Better Clinical Results Than Monotherapy in Men with Androgenetic Alopecia

January 2022 in “International Journal of Trichology”

research Pathogenesis of Androgenetic Alopecia

January 2022

Androgenetic alopecia, or hair loss, is caused by a mix of genetics, hormones, and environment, where testosterone affects hair growth and causes hair to become smaller and grow for a shorter time.

research Treatment Options for Androgenetic Alopecia: Efficacy, Side Effects, Compliance, Financial Considerations, and Ethics

17 citations, November 2021 in “Journal of Cosmetic Dermatology”

Combination therapies for androgenetic alopecia work best but can have significant side effects and costs.

research Hormonal Regulation in Male Androgenetic Alopecia: Sex Hormones and Beyond - Evidence from Recent Genetic Studies

15 citations, July 2020 in “Experimental Dermatology”

Hormones and genes affect hair growth and male baldness.

research A Study to Compare the Efficacy of Platelet-Rich Plasma and Minoxidil Therapy for the Treatment of Androgenetic Alopecia

18 citations, March 2019 in “International Journal of Trichology”

A Comparative Study of Microneedling with Platelet-Rich Plasma Plus Topical Minoxidil (5%) and Topical Minoxidil (5%) Alone in Androgenetic Alopecia

research A Comparative Study of Microneedling with Platelet-Rich Plasma Plus Topical Minoxidil (5%) and Topical Minoxidil (5%) Alone in Androgenetic Alopecia

48 citations, January 2017 in “International Journal of Trichology”

Microneedling with platelet-rich plasma and minoxidil improves hair growth more than just minoxidil in men with hair loss.

research Male Androgenetic Alopecia: Population-Based Study in 1,005 Subjects

41 citations, July 2009 in “International Journal of Trichology”

58% of men aged 30-50 have hair loss, with severity increasing with age.

research Diagnosis of Hair Disorders

73 citations, March 2009 in “Seminars in Cutaneous Medicine and Surgery”

The document concludes that accurate diagnosis of hair disorders is crucial and requires a range of diagnostic methods.

research Comparing the Therapeutic Effects of Finasteride Gel and Tablet in Treatment of Androgenetic Alopecia

57 citations, January 2009 in “Indian Journal of Dermatology, Venereology and Leprology”

8 / 8 results

research Evaluating Treatments for Male Androgenetic Alopecia: Clinical Profile and Comparative Efficacy of Platelet Rich Plasma and Minoxidil with Finasteride

September 2024 in “International Journal of Research in Dermatology”

Combining PRP with minoxidil and finasteride is the most effective treatment for male hair loss.

research Pharmacological Therapeutics in Androgenetic Alopecia

3 citations, May 2020 in “Journal of The Korean Medical Association”

Minoxidil and finasteride are effective for treating hair loss, with dutasteride showing potential but with side effects.

research Efficacy of Non-Surgical Treatments for Androgenetic Alopecia: A Systematic Review and Network Meta-Analysis

54 citations, May 2018 in “Journal of The European Academy of Dermatology and Venereology”

Low level laser therapy works best for hair loss, followed by PRP, finasteride, and minoxidil.

Combined Treatment with Oral Finasteride and Topical Minoxidil in Male Androgenetic Alopecia: A Randomized and Comparative Study in Chinese Patients

research Combined Treatment with Oral Finasteride and Topical Minoxidil in Male Androgenetic Alopecia: A Randomized and Comparative Study in Chinese Patients

32 citations, September 2015 in “Dermatologic Therapy”

Finasteride and minoxidil together work best for male hair loss.

A New Topical Formulation of Minoxidil and Finasteride Improves Hair Growth in Men with Androgenetic Alopecia