Optimal Management of Hair Loss (Alopecia) in Children

    Shannon Harrison, Rodney Sinclair
    Image of study
    The document discussed the optimal management of hair loss (alopecia) in children, emphasizing the importance of understanding hair biology and development for accurate assessment. It highlighted the significant psychological and cosmetic impacts of hair loss on children and parents. Various treatment options were reviewed, including topical corticosteroids, anthralin, minoxidil, and topical immunotherapy, with varying degrees of effectiveness. Oral corticosteroids were effective but not recommended for long-term use due to severe side effects. Conditions like tinea capitis responded well to medical therapy, while others like alopecia areata and telogen effluvium had no single effective treatment. Cosmetic solutions like wigs were recommended when no effective treatment existed. The document also covered the importance of accurate diagnosis for genetic counseling and the management of structural hair shaft abnormalities, emphasizing supportive care and minimizing hair damage.
    View this study on link.springer.com →

    Cited in this study

      CHRONIC TELOGEN EFFLUVIUM

      research CHRONIC TELOGEN EFFLUVIUM

      75 citations ,   October 1996 in “Dermatologic Clinics”
      Chronic Telogen Effluvium is a hair loss condition in middle-aged women that usually doesn't lead to complete baldness.
      Telogen Effluvium

      research Telogen Effluvium

      214 citations ,   March 1993 in “Archives of Dermatology”
      Telogen effluvium is a reversible hair loss condition that requires a detailed diagnosis and often resolves on its own.
      Alopecia Areata

      research Alopecia Areata

      49 citations ,   November 1992 in “Archives of dermatology”
      Different treatments for alopecia areata have varying success rates and side effects; intralesional steroids are most effective.
      Alopecia areata: Pathogenesis and treatment

      research Alopecia areata: Pathogenesis and treatment

      122 citations ,   November 1984 in “Journal of the American Academy of Dermatology”
      The document reviewed the pathogenesis and treatment of alopecia areata, an autoimmune condition causing hair loss. It highlighted the role of immune system dysfunction, particularly T-cell subpopulations, and their cytotoxic activities. Various treatments were explored, including systemic and topical corticosteroids, immunotherapy agents like DNCB and SADBE, and minoxidil, with varying degrees of success. While some treatments showed promise, such as photochemotherapy with a 60%-70% success rate and minoxidil with 81% effectiveness in one study, no single treatment was consistently effective. The review underscored the complexity of alopecia areata and the need for further research to improve treatment efficacy.
      Treatment of Alopecia Areata With Steroid Solution

      research Treatment of Alopecia Areata With Steroid Solution

      30 citations ,   December 1972 in “Archives of dermatology”
      The study investigated the efficacy of a high-strength steroid solution (2.5% dexamethasone in a penetration-enhancing vehicle) for treating alopecia areata in 32 patients. Group 1 (10 patients) applied the solution topically, resulting in hair regrowth in 6 patients, though 2 experienced recurrence after stopping treatment. Group 2 (22 patients) received an initial oral prednisone regimen followed by the topical solution, leading to hair regrowth in 18 patients, with 6 developing folliculitis. The study concluded that while the high-strength steroid solution could induce hair regrowth, it often caused folliculitis and comedo formation, and hair growth was not sustained in untreated control areas.
      METABOLIC DISOEDEKS AND HAIE GEOWTH

      research METABOLIC DISOEDEKS AND HAIE GEOWTH

      15 citations ,   January 1971 in “British Journal of Dermatology”
      Hair can indicate early signs of metabolic disorders, with issues like protein deficiency stopping hair growth.
      Endocrine Influences on Hair Growth

      research Endocrine Influences on Hair Growth

      68 citations ,   March 1965 in “The BMJ”
      Hormones and genetics affect hair growth and patterns, with some changes reversible and others not.
      Alopecia Totalis

      research Alopecia Totalis

      22 citations ,   March 1963 in “Archives of dermatology”
      A 34-year-old woman with alopecia totalis of 5 years duration experienced significant hair regrowth after being treated with 0.025% fluocinolone acetonide cream under an occlusive plastic dressing. The treatment involved applying the cream and covering it with a plastic film for 48 hours every 72 hours. After 3.5 months, her hair grew to 3 cm, and by September 1962, it reached 5 cm with normal texture and color. The patient showed no systemic side effects, and the treatment's success suggests that the corticosteroid acts locally, possibly facilitated by the occlusive dressing.

    Related