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    Did you mean Hair Shaft Abnormalities?
    GlossaryHair Shaft Abnormalities

    structural defects in visible hair causing fragility or unusual appearance

    Hair Shaft Abnormalities refer to structural defects in the hair shaft, the visible part of the hair that extends above the scalp. These abnormalities can result in hair that is fragile, prone to breakage, or has an unusual appearance, such as twisting, kinking, or splitting. Causes can range from genetic conditions to environmental damage or nutritional deficiencies.

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      learn GHK-Cu

      a copper peptide showing promise in both regrowth and reversing gray hair

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      signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

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      supplement to help with hair texture and quality

    Research

    5 / 1000+ results
      Structural Abnormalities of the Hair Shaft

      research Structural Abnormalities of the Hair Shaft

      126 citations, January 1987 in “Journal of The American Academy of Dermatology”
      The document concludes that understanding hair structure is key to diagnosing hair abnormalities and recommends gentle hair care for management.
      Disorders of Hair

      research Disorders of Hair

      6 citations, November 1988 in “Journal of the American Academy of Dermatology”
      The document concludes that hair analysis is not good for assessing nutrition but can detect long-term heavy metal exposure.

    Community Join

    5 / 271 results

      community Don’t Get Too Hyped About PP405. We've Seen This Movie Before.

      in Research/Science  205 upvotes 1 week ago
      PP405 is a new hair loss treatment showing early promise with a 20% hair density increase, but skepticism exists due to past failures of similar treatments like Pyrilutamide, RU58841, and Bimatoprost. Users debate its potential effectiveness, with some hopeful due to Google's involvement, while others urge caution without more evidence.

      community How does hair loss and recovery work?

      in Chat  12 upvotes 9 months ago
      Hair loss varies due to genetic sensitivity to DHT and other factors. Treatments discussed include finasteride, minoxidil, RU58841, and microneedling.

      community Wtf have we been doing for the last 30 years

      in Treatment  548 upvotes 6 months ago
      Hair loss treatments like finasteride, minoxidil, and dutasteride work but have side effects. A permanent cure is still not available due to the complexity of hair loss and limited investment.
      If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      in Research  830 upvotes 10 months ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community Verteporfin and Microneedling

      in Treatments 1 year ago
      Clinical studies by Dr. Barghouthi and Dr. Bloxham indicate that Verteporfin, when used with FUE and FUT hair transplantation methods, shows promise in hair follicle regeneration and minimal scarring due to its ability to inhibit Yes-associated protein (YAP). Microneedling at depths of 3-3.5mm, combined with Verteporfin, could potentially reactivate dormant follicles, although the optimal dosage and application method are still under investigation. Concerns remain about the DHT sensitivity of regenerated follicles, highlighting the need for further research to optimize trauma levels and Verteporfin concentrations to achieve effective and scar-free hair regeneration.