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    Glossary Hair Shaft Abnormalities

    structural defects in visible hair causing fragility or unusual appearance

    Hair Shaft Abnormalities refer to structural defects in the hair shaft, the visible part of the hair that extends above the scalp. These abnormalities can result in hair that is fragile, prone to breakage, or has an unusual appearance, such as twisting, kinking, or splitting. Causes can range from genetic conditions to environmental damage or nutritional deficiencies.

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    1. Structural abnormalities of the hair shaft Journal of The American Academy of Dermatology · 1987 · 126 citations
    2. Structural and Molecular Hair Abnormalities in Trichothiodystrophy 2006 · 71 citations
    3. Hair shaft abnormalities after chemotherapy and tamoxifen therapy in patients with breast cancer evaluated by optical coherence tomography British Journal of Dermatology · 2012 · 16 citations
    4. Hair Shaft Abnormalities – Clues to Diagnosis and Treatment Dermatology · 2005 · 44 citations
    5. Optimal Management of Hair Loss (Alopecia) in Children American Journal of Clinical Dermatology · 2003 · 49 citations
    6. Disorders of hair Journal of the American Academy of Dermatology · 1988 · 6 citations
    7. Clinical relevance of hair microscopy in alopecia Clinical and Experimental Dermatology · 2002 · 15 citations
    8. [Monilethrix--rare syndrome of structural hair abnormalities]. PubMed · 1999 · 4 citations
    9. Novel compound heterozygous mutations in the<i>desmoplakin</i>gene cause hair shaft abnormalities and culminate in lethal cardiomyopathy Clinical and Experimental Dermatology · 2014 · 5 citations
    10. Regenerative Potential of Adipose Tissue–Derived Exosomes in Treating Hair Shaft Abnormalities: A Case Report Case Reports in Dermatological Medicine · 2025
    11. Sebaceous Gland, Hair Shaft, and Epidermal Barrier Abnormalities in Keratosis Pilaris with and without Filaggrin Deficiency ˜The œAmerican journal of pathology · 2015 · 23 citations
    12. Coexisting trichorrhexis nodosa and pili annulati: a case report of hair shaft abnormalities in a syrian family Annals of Medicine and Surgery · 2024
    13. Clinical Snippets Journal of Investigative Dermatology · 2016
    14. Trichoscopy Archives of Dermatology · 2008 · 44 citations
    15. In vivo reflectance confocal microscopy: usefulness for diagnosing hair diseases Journal of Dermatological Case Reports · 2008 · 25 citations
    16. Acquired Structural Defects of the Hair International Journal of Dermatology · 1981 · 12 citations
    17. Trichoscopic Diagnosis of Structural Hair Defects in a Clinical Setting: A Cross-Sectional Analytical Study Skin Pharmacology and Physiology · 2022
    18. Hair Shafts in Trichoscopy Dermatologic Clinics · 2013 · 86 citations
    19. Angora Mouse Mutation: Altered Hair Cycle, Follicular Dystrophy, Phenotypic Maintenance of Skin Grafts, and Changes in Keratin Expression Veterinary Pathology · 1997 · 69 citations
    20. Disorders of hair in infants and children other than alopecia Clinics in dermatology · 2002 · 13 citations
    21. Hair follicle dystrophy in a litter of domestic cats resembling lanceolate hair mutant mice Veterinary dermatology · 2021 · 3 citations
    22. Trichoscopy in Hair Shaft Disorders Dermatologic Clinics · 2018 · 36 citations
    23. Hair follicle morphogenesis and epidermal homeostasis in we/we wal/wal mice with postnatal alopecia Histochemistry and Cell Biology · 2014 · 7 citations
    24. Trichoscopy CRC Press eBooks · 2015
    25. Hair Shaft Dysplasias International Journal of Dermatology · 1988 · 19 citations
    26. Isolated patchy heterochromia with pili annulati features on light and electron microscopy Dermatology practical & conceptual · 2022 · 1 citations
    27. Abnormal inner root sheath of the hair follicle in the loose anagen hair syndrome: An ultrastructural study Journal of the American Academy of Dermatology · 2010 · 31 citations
    28. Hair anatomy for the clinician Journal of The American Academy of Dermatology · 1991 · 139 citations
    29. Hair shaft disorders IP Indian Journal of Clinical and Experimental Dermatology · 2025
    30. The hair shaft: normality, abnormality, and genetics Clinics in Dermatology · 2001 · 11 citations