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    GlossaryHair Shaft Defects

    refer to structural abnormalities in hair strands

    Hair Shaft Defects refer to abnormalities in the structure of the hair strand that can lead to issues like brittleness, breakage, and an overall unhealthy appearance. These defects can be caused by genetic conditions, environmental damage, or improper hair care practices, and they often require specific treatments or changes in hair care routines to manage effectively.

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      learn Adenosine

      nucleoside used for hair regrowth stimulant properties
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      learn Valproic acid

      an anticonvulsant repurposed for hair loss via histone inhibition

      learn GHK-Cu

      a copper peptide showing promise in both regrowth and reversing gray hair

      learn HMI-115

      much-hyped research compound targeting prolactin receptor in scalp

      learn Ketoconazole

      antifungal with some anti-androgenic benefits, often used as a shampoo

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      community 6 months into Dutasteride and my hair is way worse than before

      in Finasteride/Dutasteride  77 upvotes 10 months ago
      After six months on Dutasteride, the user's hair is worse than before, despite previously trying finasteride and RU/Fluridil without success. Some suggest continuing Dutasteride and adding progress photos, while others share their positive experiences or advise sticking to one treatment for at least a year.
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      community [20M] Hair Regrowth with Minoxidil ONLY- Need Opinions

      in Minoxidil  244 upvotes 2 weeks ago
      A 20-year-old is using minoxidil for hair regrowth and considering finasteride despite concerns about side effects. Many suggest adding finasteride to maintain gains, with recommendations to start with a low dose or use a topical form to minimize side effects.
      If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      in Research  830 upvotes 5 months ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community If you are a young guy worrying about hairloss

      in Shaved/buzzed  161 upvotes 1 year ago
      A 26-year-old man embraced baldness, gaining confidence and personal growth, and encourages self-acceptance. Others discussed hair loss treatments like Minoxidil and finasteride, but he did not use them.