Cytokine Loaded Layer-By-Layer Ultrathin Matrices to Deliver Single Dermal Papilla Cells for Spot-By-Spot Hair Follicle Regeneration

    December 2015 in “ Journal of Materials Chemistry B ”
    Bojie Lin, Jin Wang, Yong Miao … Malcolm Xing
    Studysummary This study found that using layer-by-layer encapsulation techniques on dermal papilla cells can support their function and may help treat hair loss when used in conjunction with freshly isolated epidermal cells.
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    Research cited in this study 22

    1. A Simple and Rapid Model for Hair-Follicle Regeneration in the Nude Mouse Clinical and Experimental Dermatology · 2015
    2. Controllable Production of Transplantable Adult Human High-Passage Dermal Papilla Spheroids Using 3D Matrigel Culture Tissue engineering. Part A · 2014
    3. Emerging Interactions Between Skin Stem Cells and Their Niches Nature Medicine · 2014
    4. Regenerative Medicine and Hair Loss: How Hair Follicle Culture Has Advanced Our Understanding of Treatment Options for Androgenetic Alopecia Regenerative Medicine · 2013
    5. Microenvironmental Reprogramming by Three-Dimensional Culture Enables Dermal Papilla Cells to Induce De Novo Human Hair-Follicle Growth Proceedings of the National Academy of Sciences of the United States of America · 2013
    6. Follicular Dermal Papilla Structures by Organization of Epithelial and Mesenchymal Cells in Interfacial Polyelectrolyte Complex Fibers Biomaterials · 2013
    7. Strategies to Enhance Epithelial-Mesenchymal Interactions for Human Hair Follicle Bioengineering Journal of Dermatological Science · 2013
    8. 6-Gingerol Inhibits Hair Shaft Growth in Cultured Human Hair Follicles and Modulates Hair Growth in Mice PLOS ONE · 2013
    9. Scalable Production of Controllable Dermal Papilla Spheroids on PVA Surfaces and the Effects of Spheroid Size on Hair Follicle Regeneration Biomaterials · 2012
    10. Fully Functional Hair Follicle Regeneration Through the Rearrangement of Stem Cells and Their Niches Nature Communications · 2012
    11. Clonal Growth of Dermal Papilla Cells in Hydrogels Reveals Intrinsic Differences Between Sox2-Positive and Sox2-Negative Cells In Vitro and In Vivo Journal of Investigative Dermatology · 2011
    12. De Novo Formation and Ultra-Structural Characterization of a Fiber-Producing Human Hair Follicle Equivalent In Vitro Journal of biotechnology · 2011
    13. Beta-Catenin Activity in the Dermal Papilla Regulates Morphogenesis and Regeneration of Hair Developmental Cell · 2010
    14. Review of Hair Follicle Dermal Cells Journal of Dermatological Science · 2009
    15. A Human Folliculoid Microsphere Assay for Exploring Epithelial-Mesenchymal Interactions in the Human Hair Follicle ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2008
    16. Cultured Peribulbar Dermal Sheath Cells Can Induce Hair Follicle Development and Contribute to the Dermal Sheath and Dermal Papilla Journal of Investigative Dermatology · 2003
    17. Plasticity and Cytokinetic Dynamics of the Hair Follicle Mesenchyme: Implications for Hair Growth Control Journal of Investigative Dermatology · 2003
    18. In Vivo Promoted Growth of Mice Hair Follicles by the Controlled Release of Growth Factors Biomaterials · 2003
    19. Molecular Mechanisms Regulating Hair Follicle Development ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2002
    20. The Psychosocial Consequences of Androgenetic Alopecia: A Review of the Research Literature British Journal of Dermatology · 1999
    21. The Biology of Hair Follicles The New England Journal of Medicine · 1999
    22. Effects of Epidermal Growth Factor, Fibroblast Growth Factor, Minoxidil, and Hydrocortisone on Growth Kinetics in Human Hair Bulb Papilla Cells and Root Sheath Fibroblasts Cultured In Vitro Archives of Dermatological Research · 1987

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