Receptor Activator of NF-κB Stimulates the Proliferation of Epithelial Cells of the Epidermo-Pilosebaceous Unit

    March 2011 in “ Proceedings of the National Academy of Sciences of the United States of America ”
    Vincent Duhéron, Estelle Hess, Monique Duval … Christopher G. Mueller
    Studysummary This study found that RANK-RANKL signaling regulates hair renewal and epidermal homeostasis in mice, revealing its role in initiating hair growth cycles and maintaining skin cell activity.
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    Research cited in this study 15

    1. The Hair Follicle as a Dynamic Mini-Organ Current Biology · 2009
    2. Analyses of Regenerative Wave Patterns in Adult Hair Follicle Populations Reveal Macro-Environmental Regulation of Stem Cell Activity ˜The œInternational journal of developmental biology · 2009
    3. Lgr5 Marks Cycling, Yet Long-Lived, Hair Follicle Stem Cells Nature Genetics · 2008
    4. TNF Superfamily in Skin Appendage Development Cytokine & growth factor reviews · 2008
    5. Hormonal Regulation of Hair Follicles Exhibits a Biological Paradox Seminars in Cell & Developmental Biology · 2007
    6. Scratching the Surface of Skin Development Nature · 2007
    7. Epithelial Stem Cells: Turning Over New Leaves Cell · 2007
    8. Role of the Vitamin D Receptor in Hair Follicle Biology The Journal of Steroid Biochemistry and Molecular Biology · 2007
    9. Premature Termination of Hair Follicle Morphogenesis and Accelerated Hair Follicle Cycling in Iasi Congenital Atrichia (fzica) Mice Points to Fuzzy as a Key Element of Hair Cycle Control Experimental dermatology · 2005
    10. Prolactin and Its Receptor Are Expressed in Murine Hair Follicle Epithelium, Show Hair Cycle-Dependent Expression, and Induce Catagen American Journal of Pathology · 2003
    11. Selective Expression of Calcium-Binding Proteins S100A8 and S100A9 at Distinct Sites of Hair Follicles Journal of Investigative Dermatology · 2001
    12. Skin Abnormalities Generated by Temporally Controlled RXRα Mutations in Mouse Epidermis Nature · 2000
    13. The Biology of Hair Follicles The New England Journal of Medicine · 1999
    14. Dermal-Epidermal Interactions in Hair Follicle Development and Maintenance Dermatologic clinics · 1996
    15. Cells Within the Bulge Region of Mouse Hair Follicle Transiently Proliferate During Early Anagen: Heterogeneity and Functional Differences of Various Hair Cycles Differentiation · 1994

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