Lichen planopilaris: retrospective study on the characteristics and treatment of 291 patients
January 2019
in “
Journal of dermatological treatment
”
TLDR Women are more likely to have Lichen planopilaris, and treatments with cyclosporine and methotrexate are most effective but less safe than mycophenolate mofetil.
The retrospective study on 291 patients with lichen planopilaris (LPP) conducted by the Autoimmune Bullous Diseases Research Center at Tehran University of Medical Sciences aimed to characterize the disease and evaluate treatment outcomes. The study found that LPP predominantly affected middle-aged women and was associated with significant hair loss and scarring. Various treatments were assessed, including corticosteroids and immunosuppressive agents, with varying degrees of success. The study highlighted the chronic nature of LPP and the need for ongoing management to control symptoms and prevent progression.
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