12 citations
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December 2021 in “Frontiers in Medicine” This study observed that dermatological patients using certain immunosuppressants, like azathioprine and high-dose prednisolone, had a reduced humoral immune response to the Sinovac-CoronaVac COVID-19 vaccine compared to those without such treatments.
54 citations
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July 1994 in “Journal of Dermatological Science” This study found that topical application of FK506 stimulated hair growth in animals, which may occur independently of its immunosuppressive effects, though its effect on human hair growth remains unclear.
1 citations
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July 2020 in “Journal of cosmetic dermatology” This case report describes a patient with systemic lupus erythematosus who developed both alopecia areata and lichen planopilaris despite immunosuppressive treatment, suggesting a shared immunopathogenesis between these disorders.
August 2025 in “International Journal of Research in Dermatology” This study found that adding cyclophosphamide to glucocorticoid treatment for pemphigus patients led to earlier remission, with 89.5% achieving remission within 4 months compared to 73.9% with glucocorticoids alone, suggesting significant steroid-sparing effects and improved clinical outcomes.
116 citations
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October 1982 in “The Journal of Pathology” This study found that high-dose Cyclosporin A in rats led to significant functional and structural changes, including liver, kidney, and immune system alterations, along with behavioral and hematological effects.