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    Dissection of Genetic Variation and Evidence for Pleiotropy in Male Pattern Baldness

    December 2018 in “ Nature Communications ”
    Chloe X. Yap, Julia Sidorenko, Yang Wu … Peter M. Visscher
    Studysummary This study found that male pattern baldness in European males is strongly heritable and associated with genetic markers linked to earlier puberty, bone density, and pancreatic function.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 20

    1. GWAS for Male-Pattern Baldness Identifies 71 Susceptibility Loci Explaining 38% of the Risk Nature Communications · 2017
    2. Meta-Analysis Identifies Novel Risk Loci and Yields Systematic Insights into the Biology of Male-Pattern Baldness Nature communications · 2017
    3. Genetic Prediction of Male Pattern Baldness PLoS Genetics · 2017
    4. Hunting the Genes in Male-Pattern Alopecia: How Important Are They, How Close Are We and What Will They Tell Us? Experimental Dermatology · 2016
    5. Classifications of Patterned Hair Loss: A Review Journal of Cutaneous and Aesthetic Surgery · 2016
    6. Is Early Onset Androgenic Alopecia a Marker of Metabolic Syndrome and Carotid Artery Atherosclerosis in Young Indian Male Patients? International Journal of Trichology · 2015
    7. Androgen Actions on the Human Hair Follicle: Perspectives Experimental Dermatology · 2012
    8. Six Novel Susceptibility Loci for Early-Onset Androgenetic Alopecia and Their Unexpected Association with Common Diseases PLOS Genetics · 2012
    9. Susceptibility Variants on Chromosome 7p21.1 Suggest HDAC9 as a New Candidate Gene for Male-Pattern Baldness British Journal of Dermatology · 2011
    10. Recent Positive Selection of a Human Androgen Receptor/Ectodysplasin A2 Receptor Haplotype and Its Relationship to Male Pattern Baldness Human Genetics · 2009
    11. Androgenetic Alopecia and Insulin Resistance in Young Men Clinical Endocrinology · 2008
    12. Susceptibility Variants for Male-Pattern Baldness on Chromosome 20p11 Nature Genetics · 2008
    13. Male-Pattern Baldness Susceptibility Locus at 20p11 Nature Genetics · 2008
    14. EDA2R Is Associated With Androgenetic Alopecia Journal of Investigative Dermatology · 2008
    15. Genetic Variation in the Human Androgen Receptor Gene Is the Major Determinant of Common Early-Onset Androgenetic Alopecia American Journal of Human Genetics · 2005
    16. The E211 G>A Androgen Receptor Polymorphism Is Associated With a Decreased Risk of Metastatic Prostate Cancer and Androgenetic Alopecia Cancer Epidemiology, Biomarkers & Prevention · 2005
    17. Genetic Basis of Male Pattern Baldness Journal of Investigative Dermatology · 2003
    18. Polymorphism of the Androgen Receptor Gene Is Associated with Male Pattern Baldness Journal of Investigative Dermatology · 2001
    19. Androgens and Human Hair Growth Clinical endocrinology · 1994
    20. Androgenetic Alopecia: Pathophysiological Aspects in Man and Animals Springer eBooks · 1990