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research Do Pleiotropic Effects of Spironolactone in Women With PCOS Make It More Than an Anti-Androgen? Evidence From a Systematic Review and Meta-Analysis

March 2023 in “Current Pharmaceutical Design”

Spironolactone is effective for idiopathic hirsutism but has limited effects on other PCOS symptoms.

research Into the Redox Control: N-Acetyl-Cysteine Pleiotropic Effects from the Laboratory to Clinical Applications

4 citations, December 2013 in “Acupuncture and related therapies”

N-acetyl-cysteine shows promise in treating various diseases and may improve skin and hair conditions, but more research is needed on dosages and long-term effects.

research Wnt Signaling and Aging-Related Heart Disorders

59 citations, November 2010 in “Circulation Research”

Wnt signaling may be linked to heart diseases in aging and could be a target for future treatments.

research The Exaptation of Endocrine Pharmacology

6 citations, January 2012 in “Indian Journal of Endocrinology and Metabolism”

Old drugs are often used for new, different medical purposes in endocrine pharmacology.

research Dissection of Genetic Variation and Evidence for Pleiotropy in Male Pattern Baldness

58 citations, December 2018 in “Nature Communications”

Male pattern baldness is mostly inherited, involves many genes, and is linked to other traits like early puberty and strong bones.

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community The Real Cause Of Androgenetic Alopecia

in Research/Science 667 upvotes 1 month ago

Androgenetic alopecia is caused by DHT affecting hair growth. Finasteride and minoxidil are used to manage hair loss by blocking DHT and promoting hair growth.

community Watching my younger brother bald hurts so much.

in Treatment 264 upvotes 3 months ago

A 19-year-old is distressed about his 17-year-old autistic brother's hair loss, projecting his own insecurities despite being on finasteride and dutasteride. Replies suggest the brother might not care about balding, and the poster should address his own issues.