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Spironolactone is effective for idiopathic hirsutism but has limited effects on other PCOS symptoms.

N-acetyl-cysteine shows promise in treating various diseases and may improve skin and hair conditions, but more research is needed on dosages and long-term effects.

Wnt signaling may be linked to heart diseases in aging and could be a target for future treatments.

Old drugs are often used for new, different medical purposes in endocrine pharmacology.

Male pattern baldness is mostly inherited, involves many genes, and is linked to other traits like early puberty and strong bones.

Laminaria japonica extract with IGF-1 improved mouse hair growth and could be a potential alopecia treatment.

Mutations in the hairless gene in mice affect its expression and lead to a range of developmental issues in multiple tissues.

The document concludes that certain mutations may contribute to the inflammation in hidradenitis suppurativa and suggests that targeting TNFα could be a treatment strategy.

Androgens, male hormones, affect physical and mental functions, with a decrease leading to health issues like muscle loss, bone disease, and depression, and more research is needed on long-term effects and treatments.

Caffeine may help reduce stress-induced hair loss.

Metformin is less effective in men with early-onset hair loss.

Omega-6 and LDL cholesterol increase the risk of hair loss.

Negative pressure therapy increases hair growth in mice.

Higher testosterone levels can increase the risk of certain diseases like type 2 diabetes in women and prostate cancer in men, but can also protect against autoimmune diseases and hair loss. It also affects body fat and bone density.

Long-term high testosterone levels can improve bone density and reduce body fat but may increase the risk of prostate cancer and high blood pressure.

Increased free testosterone can lead to stronger bones and less body fat but also higher risks of prostate cancer, hair loss, spine issues, and high blood pressure.

New method finds genetic links between Type 2 Diabetes and Prostate Cancer not seen before.

Researchers found genes and genetic variants linked to sheep wool and skin wrinkles.

Finasteride can have lasting negative effects on brain function and behavior by disrupting neurosteroid production.

Early recognition and management of skin side effects from new cancer therapies can prevent treatment delays.

Topical vitamin D is effective in treating vitiligo with few side effects.

Tofacitinib helped a person with total body hair loss grow hair again without bad side effects.

Different drugs can treat high male hormone levels in women, but they have various effects and some may harm a fetus.

The Rotterdam Study updated findings on elderly health, focusing on heart disease, genetics, lifestyle effects, and disease understanding.

The Rotterdam Study found risk factors for elderly diseases, links between lifestyle and genetics with health conditions, and aimed to explore new areas like DNA methylation and sensory input effects on brain function.

Different human traits like skin color and hair type vary between populations due to genetic adaptations to the environment.

The nude gene causes skin cell overgrowth and improper development, leading to hair and urinary issues.

The L457(3.43)R mutation in the human lutropin receptor causes increased activity and hormone insensitivity, leading to precocious puberty.

Rosuvastatin improves lipid levels, reduces inflammation, but worsens insulin sensitivity in men with early-onset hair loss.

Metformin helps improve skin regeneration by increasing the growth of skin stem cells.