research Exogenous Stimulation with Eclipta Alba Promotes Hair Matrix Keratinocyte Proliferation and Downregulates TGF-β1 Expression in Nude Mice
Eclipta alba extract helps increase hair growth and decrease hair loss-related protein in mice.
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research In Vivo Hair Growth-Stimulating Effect of Medicinal Plant Extract on BALB/c Nude Mice
Chrysanthemum zawadskii extract may be a better treatment for hair loss than Minoxidil.
research Towards Dissecting the Pathogenesis of Retinoid-Induced Hair Loss: All-Trans Retinoic Acid Induces Premature Hair Follicle Regression by Upregulation of Transforming Growth Factor-β2 in the Dermal Papilla
All-trans retinoic acid causes hair loss by increasing TGF-β2 in hair follicle cells.
research RANK as a Therapeutic Target in Cancer
RANK is a key target in breast cancer treatment due to its role in tumor growth and bone metastasis.
research Off-Label Uses of Retinoids in Dermatology
Retinoids are effective for various skin conditions and hair loss but have serious side effects, so low doses are recommended.
research Recent Advances in the Molecular Mechanisms Determining Tissue Sensitivity to Glucocorticoids: Novel Mutations, Circadian Rhythm, and Ligand-Induced Repression of the Human Glucocorticoid Receptor
New findings explain how genetic changes, body clocks, and certain molecules affect tissue response to stress hormones.
research The Effect of Alfacalcidiol and Metformin on Metabolic Disturbances in Women with Polycystic Ovary Syndrome
Metformin effectively improves metabolic symptoms in women with PCOS, while alfacalcidiol does not have a significant impact.
research Repurposing of Approved Cardiovascular Drugs
Some heart drugs show promise for other conditions, but more research is needed to confirm their effectiveness and safety.
research Cyclosporin A-Induced Hair Growth in Mice Is Associated with Inhibition of Calcineurin-Dependent Activation of NFAT in Follicular Keratinocytes
Cyclosporin A helps mice grow hair by blocking a specific protein activity in skin cells.
research An In Vitro Model for the Morphogenesis of Hair Follicle Dermal Papillae
Scientists created a model using sheep cells to study hair root formation, which can test how different substances affect hair growth.
research Perturbations in Fatty Acid Metabolism and Collagen Production Infer Pathogenicity of a Novel MBTPS2 Variant in Osteogenesis Imperfecta
A new MBTPS2 gene variant disrupts fat metabolism and collagen production, causing Osteogenesis imperfecta.
research Skin Endocrinology and Nutrition
Good nutrition and vitamins are important for healthy skin and can prevent diseases.
research Chemically Induced Depigmentation of Skin and Hair
Some chemicals can permanently or temporarily remove color from skin and hair, which can be distressing and is not well-regulated in cosmetics.
research A Comprehensive Review on Metabolic Syndrome
Managing metabolic syndrome needs both lifestyle changes and medical treatments.
research Teriflunomide and Its Mechanism of Action in Multiple Sclerosis
Teriflunomide helps reduce multiple sclerosis symptoms and is safe for most patients.
research Extraskeletal Actions of Vitamin D
Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.
research Repurposing Existing Drugs for COVID-19: An Endocrinology Perspective
Existing drug dexamethasone may lower death risk in severe COVID-19 cases; more research needed for other drugs.
research Role of Beta-Catenin Activation Levels and Fluctuations in Controlling Cell Fate
Proper control of β-catenin activity is crucial for development and preventing diseases like cancer.
research Update on the Use of Topical Calcineurin Inhibitors in Cutaneous Lupus Erythematosus
Topical calcineurin inhibitors, especially 0.1% tacrolimus ointment, are effective and well-tolerated for treating cutaneous lupus erythematosus but require more research for standard treatment guidelines.
research Pharmacological and Phytochemical Updates on Citrullus Colocynthis and Citrullus Lanatus
Citrullus colocynthis and Citrullus lanatus have potential health benefits but may also cause reproductive toxicity.
research The Important Role of Leptin in Modulating the Risk of Dermatological Diseases
Leptin, a hormone from fat cells, affects immune responses and can influence skin diseases and hair growth.
research An Epistatic Effect of KRT25 on SP6 Is Involved in Curly Coat in Horses
The genes KRT25 and SP6 affect curly hair in horses, with KRT25 also causing hair loss. If both genes are mutated, the horse gets curly hair and hair loss. KRT25 can hide the effect of SP6.
research The Secretome of Irradiated Peripheral Mononuclear Cells Attenuates Hypertrophic Skin Scarring
PBMCsec can help reduce and improve thick skin scars.
research Finasteride Delays Atherosclerosis Progression in Mice and Is Associated With a Reduction in Plasma Cholesterol in Men
Finasteride may lower cholesterol and slow heart disease progression.
research Exploring the Relationship Between Immune Cells and Non-Scarring Hair Loss: A Mendelian Randomization Study
Certain immune cells are linked to non-scarring hair loss, suggesting potential for immune-targeted treatments.
research Revisiting the Role of Melatonin in Human Melanocyte Physiology: A Skin Context Perspective
Melatonin affects skin and hair color and protects skin cells, with potential benefits for hair growth and skin health.
research DPP-4 Inhibition with Linagliptin Ameliorates the Progression of Premature Aging in Klotho−/− Mice
Linagliptin slows down premature aging in certain mice.
research Exome-Wide Age-of-Onset Analysis Reveals Exonic Variants in ERN1, TACR3, and SPPL2C Associated with Alzheimer’s Disease
Certain genetic variants in ERN1, TACR3, and SPPL2C are linked to when Alzheimer's disease starts.
research Genetically Modified Laboratory Mice with Sebaceous Glands Abnormalities
Genetic changes in mice help understand skin and hair disorders, aiding treatment development for acne and hair loss.
research Association of Atopic Dermatitis With Autoimmune Diseases: A Bidirectional and Multivariable Two-Sample Mendelian Randomization Study
Atopic dermatitis increases the risk of some autoimmune diseases.