The Genetic Link Between Thyroid Dysfunction And Alopecia Areata: A Bidirectional Two-Sample Mendelian Randomization Study

    August 2024 in “ Frontiers in Endocrinology ”
    Le Gao, Wenrui Li, Qiang Song … Mingwei Chen
    Studysummary This study offers genetic evidence supporting a causal relationship between thyroid dysfunction and alopecia areata, which may help in managing and treating AA patients.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 20

    1. Deciphering the Complex Immunopathogenesis of Alopecia Areata International Journal of Molecular Sciences · 2024
    2. Characteristics and Management of Patients with Alopecia Areata and Selected Comorbid Conditions: Results from a Survey in Five European Countries Dermatology and therapy · 2024
    3. Mendelian Randomization Study Highlights Hypothyroidism as a Causal Determinant of Alopecia Areata Frontiers in endocrinology · 2024
    4. Is Thyroid Dysfunction a Common Cause of Telogen Effluvium? A Retrospective Study Medicine · 2024
    5. Impact of Thyroid Dysfunction on Hair Disorders Cureus · 2023
    6. Comorbid Conditions Associated With Alopecia Areata: A Systematic Review and Meta-Analysis American Journal of Clinical Dermatology · 2023
    7. Study of the Thyroid Profile of Patients with Alopecia Journal of Clinical Medicine · 2023
    8. Thyroid Hormone Receptor Agonist Promotes Hair Growth in Mice Clinical, Cosmetic and Investigational Dermatology · 2022
    9. Prevalence and Risk Factors Associated with the Occurrence of Autoimmune Diseases in Patients with Alopecia Areata Journal of Inflammation Research · 2021
    10. Alopecia Areata: An Autoimmune Disease of Multiple Players ImmunoTargets and therapy · 2021
    11. Hormonal Effects on Hair Follicles International journal of molecular sciences · 2020
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    13. Hair Regrowth Outcomes of Contact Immunotherapy for Patients With Alopecia Areata JAMA Dermatology · 2018
    14. Alopecia Areata: A Review of Disease Pathogenesis British journal of dermatology/British journal of dermatology, Supplement · 2018
    15. Alopecia Areata: Overview and Insights from January 2018 Journal of The American Academy of Dermatology · 2017
    16. Intestinal Dysbiosis and Biotin Deprivation Induce Alopecia Through Overgrowth of Lactobacillus Murinus in Mice Cell Reports · 2017
    17. Organ Specificity in Autoimmune Diseases: Thyroid and Islet Autoimmunity in Alopecia Areata The Journal of Clinical Endocrinology & Metabolism · 2015
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    20. Thyroid Hormone Receptor β1 Is Expressed in the Human Hair Follicle British journal of dermatology/British journal of dermatology, Supplement · 2000