Traditional Review: Exosomes in Dermatology and Cosmetology

    March 2026 in “ Akdeniz Medical Journal ”
    Koray Durmaz, Pınar Öztaş
    TLDR Exosomes show promise for treating skin conditions and improving cosmetic skin health.
    This review explores the potential of exosomes as a non-cellular therapeutic option in dermatology and cosmetology. Exosomes are nanovesicles that facilitate intercellular communication and carry bioactive substances, showing promise in modulating cell microenvironments, regulating gene expression, and inducing cell differentiation. They have been used to promote tissue regeneration in skin wounds and treat conditions like systemic lupus erythematosus, psoriasis, atopic dermatitis, systemic sclerosis, pigment regulation, vitiligo, and hair growth. Cosmetically, exosomes help reduce wrinkles, improve skin texture and moisture, enhance elasticity, and mitigate UV-induced inflammation and cellular damage. The review suggests further research to expand their applications.
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