Exosomes based advancements for application in medical aesthetics

Exosomes, nano vesicles secreted by cells, have potential applications in medical aesthetics, particularly in wound repair, anti-aging, hyperpigmentation inhibition, and hair loss prevention. They promote wound repair, reduce inflammation, accelerate tissue remodeling, and inhibit scar formation. They can also regulate gene expression. For hair loss, exosomes can induce hair follicle regeneration by promoting the proliferation of dermal papilla cells and affecting hair follicle signaling pathways. Topical application or local injection of exosomes can be enhanced by microneedles or transdermal drug delivery. However, the field is still in the early stages of research, and challenges remain due to the high cost of separation procedures, low purity of exosomes, and the need for appropriate storage methods. Future research is needed to determine the ideal storage conditions for exosomes, improve their efficacy, and develop large-scale preparation technology.