Effects of a Closed Space Environment on Gene Expression in Hair Follicles of Astronauts in the International Space Station

    March 2016 in “ PloS one ”
    Masahiro Terada, Masayuki Seki, Rika Takahashi … Noriaki Ishioka
    Studysummary This study found that spaceflight alters gene expression in human hair follicles, with variations among astronauts, and suggests that spaceflight may inhibit cell proliferation in hair follicles.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
    Read the full study on journals.plos.org →
    Discuss this study in the Community →

    Research cited in this study 14

    1. Skin Physiology in Microgravity: A 3-Month Stay Aboard ISS Induces Dermal Atrophy and Affects Cutaneous Muscle and Hair Follicles Cycling in Mice NPJ microgravity · 2015
    2. Epidermal Wnt/β-Catenin Signaling Regulates Adipocyte Differentiation via Secretion of Adipogenic Factors Proceedings of the National Academy of Sciences of the United States of America · 2014
    3. Signaling Involved in Hair Follicle Morphogenesis and Development International Journal of Molecular Sciences · 2014
    4. Hair Cycle Resting Phase Is Regulated by Cyclic Epithelial FGF18 Signaling Journal of Investigative Dermatology · 2012
    5. Effect of IGF-I on Hair Growth Is Related to the Anti-Apoptotic Effect of IGF-I and Up-Regulation of PDGF-A and PDGF-B Annals of Dermatology · 2012
    6. Cartilage Oligomeric Matrix Protein Forms Part of the Connective Tissue of Normal Human Hair Follicles Experimental dermatology · 2011
    7. Noninvasive Method for Assessing the Human Circadian Clock Using Hair Follicle Cells Proceedings of the National Academy of Sciences of the United States of America · 2010
    8. PDGF Isoforms Induce and Maintain Anagen Phase of Murine Hair Follicles Journal of Dermatological Science · 2006
    9. Extraction and Detection of mRNA from Horsehair Journal of veterinary medical science · 2006
    10. Characterization and Isolation of Stem Cell-Enriched Human Hair Follicle Bulge Cells ˜The œJournal of clinical investigation/˜The œjournal of clinical investigation · 2005
    11. The Biology of Hair Follicles The New England Journal of Medicine · 1999
    12. The Secret Life of the Hair Follicle Trends in genetics · 1992
    13. Hair Anatomy for the Clinician Journal of The American Academy of Dermatology · 1991
    14. Trichotillometry: The Quantitation of Hair Pluckability as a Method of Nutritional Assessment American Journal of Clinical Nutrition · 1981