Effects of Aucklandia Lappa Decne. Extract on Hair Growth in Depilated CL57BL/6 Mice

March 2021 in “ Korean Journal of Clinical Laboratory Science ”

Joung-Hee Kim, Syng‐Ook Lee, Gyoung Yeun Beik, Keuk‐Jun Kim

Aucklandia lappa hair growth polyphenol cell viability nitric oxide inhibition collagen production hair loss

TLDR The extract promoted hair growth without significant toxicity.

The study investigated the effects of Aucklandia lappa Decne. extract on hair growth in depilated CL57BL/6 mice. The extract was prepared using a 70% prethanol solution and tested for polyphenol content, cell viability, and nitric oxide inhibition. Mice were divided into groups and given the extract orally for 6 weeks. Hair growth and weight changes were monitored, and tissue samples were analyzed for toxicity and collagen production. Results showed that the extract promoted hair growth without significant toxicity, suggesting its potential as a treatment for hair loss.

View this study on kjcls.org →

Discuss this study in the Community →

Research cited in this study

10 / 10 results

research A Guide to Studying Human Hair Follicle Cycling In Vivo

212 citations, September 2015 in “Journal of Investigative Dermatology”

The document provides a method to classify human hair growth stages using a model with human scalp on mice, aiming to standardize hair research.

research Fibroblast Growth Factors Stimulate Hair Growth Through Beta-Catenin and Shh Expression in C57BL/6 Mice

64 citations, January 2015 in “BioMed Research International”

Certain growth factors can promote hair growth in mice by activating hair growth-related proteins.

research Drugs and Hair Loss: Mechanisms and Clinical Implications

54 citations, September 2012 in “Dermatologic Clinics”

Some medications can cause hair loss, but stopping the drug usually leads to recovery within 3 months.

research Therapeutic Anti-Inflammatory Potential of Formyl-Peptide Receptor Agonists

105 citations, August 2010 in “Pharmacology & therapeutics”

Formyl-peptide receptor agonists could be new anti-inflammatory drugs.

research Hair Growth Promoting Effect of Zizyphus Jujuba Essential Oil

73 citations, March 2010 in “Food and Chemical Toxicology”

Zizyphus jujuba essential oil can promote hair growth.

research Targeting to the Hair Follicles: Current Status and Potential

142 citations, January 2010 in “Journal of dermatological science”

Hair follicles are promising targets for delivering drugs effectively.

research Effect of Sodium Silicate on Hair Growth in C57BL/6 Mice

4 citations, January 2010 in “Laboratory Animal Research”

Sodium silicate helped mouse hair grow similarly to a known hair growth treatment.

research Identification of novel hair‐growth inducers by means of connectivity mapping

30 citations, December 2009 in “The FASEB Journal”

research Growth Factors in Hair Organ Development and the Hair Growth Cycle

90 citations, October 1996 in “Dermatologic Clinics”

Growth factors are crucial for hair development and could help treat hair diseases.

research BIOCHEMICAL ANALYSIS OF HAIR GROWTH FROM THE ASPECTS OF AGING AND ENZYME ACTIVITIES

46 citations, February 1983 in “The Journal of Dermatology”

Similar Research

5 / 93 results

research Costunolide: A Bioactive Sesquiterpene Lactone with Diverse Therapeutic Potential

75 citations, June 2019 in “International Journal of Molecular Sciences”

Costunolide may have multiple health benefits, including promoting hair growth and protecting against cancer and diabetes, but more research is needed.

research Combination of Western Medicine and Traditional Chinese Medicine for Treatment of Malignant Bone and Soft Tissue Tumors

1 citations, February 2018 in “Orthopedics and rheumatology”

Combining Western chemotherapy with Traditional Chinese Medicine can reduce side effects and improve immune response in treating bone and soft tissue tumors.

research Immunohistochemical Study on the Hair Growth Promoting Effect of Yonnyuniksoogobon-Dan

1 citations, November 2008

Yonnyuniksoogobon-dan taken orally promotes hair growth by affecting growth factors in hair roots.

research The Pill: Pimples, Pigmentation, and Alopecia?

March 1988 in “Reactions (Auckland)”

Birth control pills can improve or cause acne and hair issues, with improvements more common, and may affect skin pigmentation.

research Cefalexin

January 1988 in “Reactions (Auckland)”

A woman developed a severe skin reaction from the antibiotic cefalexin.