A Retrospective Comparative Study of Two Concentrations of Intralesional Triamcinolone Acetonide in the Treatment of Patchy Alopecia Areata on the Scalp

The study compared the efficacy of two concentrations of intralesional triamcinolone acetonide (5 mg/mL and 10 mg/mL) in treating patchy alopecia areata on the scalp in 85 patients. Both concentrations were found to be equally effective in achieving satisfactory hair regrowth at 12 weeks, though the 10 mg/mL concentration induced faster results at 4 weeks. Side effects were slightly more common in the 10 mg/mL group but were not statistically significant. Approximately 48% of patients achieved complete hair regrowth, and 70% experienced satisfactory results after 1-3 injections. Recurrence occurred in about half of the patients after 1-3 years, regardless of the ILT dose or prognostic factors. Longer disease duration (>6 months) negatively impacted treatment response. The study suggested that using the 5 mg/mL concentration could limit exposure to side effects while covering a wider surface area.