In Vitro Anti-Melanoma Activity and In Vivo Hair Growth Stimulation by Lophocereus Marginatus Methanol Extracts

    September 2025 in “ Journal of King Saud University - Science ”
    Ricardo Gomez‐Flores, Ángel David Torres-Hernández, Claudia Sarahí Villarreal-Salcido … Carmen López Sáenz
    Studysummary This study found that Lophocereus marginatus extracts significantly inhibited melanoma cell growth in vitro and stimulated hair growth in mice, with combined treatments of LM with minoxidil or bergamot showing notable effects by day 14 without altering body weight.
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    Research cited in this study 19

    1. Integrative and Mechanistic Approach to the Hair Growth Cycle and Hair Loss Journal of Clinical Medicine · 2023
    2. An Overview of the Genetic Aspects of Hair Loss and Its Connection with Nutrition PubMed · 2022
    3. Anti-Invasive Effects of Minoxidil on Human Breast Cancer Cells: Combination with Ranolazine Clinical & Experimental Metastasis · 2022
    4. Identification of Beta-Sitosterol and Stigmasterol as Possible Inhibitors of 5 Alpha-Reductase 1: An In-Silico Study Precision medicine and clinical omics · 2022
    5. Advances in Hair Growth Faculty reviews · 2022
    6. Anti-Inflammatory, Thrombolytic, and Hair-Growth Promoting Activity of the n-Hexane Fraction of the Methanol Extract of Leea Indica Leaves Plants · 2021
    7. Efficacy and Safety of Oral Minoxidil 5 mg Once Daily in the Treatment of Male Patients with Androgenetic Alopecia: An Open-Label and Global Photographic Assessment Dermatology and therapy · 2020
    8. Herbal Medicines for Treatment of Androgenic Alopecia PubMed · 2020
    9. Hair Matters in Melanoma Biology Trends in molecular medicine · 2020
    10. Herbal Preparations for the Treatment of Hair Loss Archives of Dermatological Research · 2019
    11. Minoxidil And Its Use In Hair Disorders: A Review Drug Design Development and Therapy · 2019
    12. Efficacy of Bergamot: From Anti-Inflammatory and Anti-Oxidative Mechanisms to Clinical Applications as a Preventive Agent for Cardiovascular Morbidity, Skin Diseases, and Mood Alterations Food science & nutrition · 2019
    13. A Comparative Study to Test a Plant Extract Against Minoxidil in HaCaT Cells Journal of Dermatology and Venereology · 2017
    14. Epidemiology and Burden of Alopecia Areata: A Systematic Review Clinical, Cosmetic and Investigational Dermatology · 2015
    15. In Vivo Hair Growth-Stimulating Effect of Medicinal Plant Extract on BALB/c Nude Mice Pharmaceutical Biology · 2015
    16. Promotive Effect of Topical Ketoconazole, Minoxidil, and Minoxidil with Tretinoin on Hair Growth in Male Mice ISRN Pharmacology (Print) · 2014
    17. Promotion of Hair Growth by Rosmarinus Officinalis Leaf Extract Phytotherapy Research · 2012
    18. Promotive Effect of Minoxidil Combined with All-Trans Retinoic Acid (Tretinoin) on Human Hair Growth In Vitro Journal of Korean Medical Science · 2007
    19. Drug-Induced Hair Loss and Hair Growth Drug Safety · 1994