53 citations
,
February 2020 in “Expert Opinion on Pharmacotherapy” This review discusses pharmacologic and non-pharmacologic treatments for androgenetic alopecia, noting that current medications like finasteride and minoxidil can slow hair loss but only partially restore hair growth, with early treatment offering better outcomes.
8 citations
,
April 2019 in “Dermatologic Therapy” This study found that applying topical tretinoin can influence follicular sulfotransferase expression, enabling 43% of predicted nonresponders to minoxidil to respond positively in the context of androgenetic alopecia.
12 citations
,
September 2018 in “Dermatologic Therapy” This study found that 14 days of low-dose aspirin reduced the predicted response to topical minoxidil in androgenetic alopecia patients from 50% to 27%, suggesting aspirin may inhibit minoxidil efficacy.
36 citations
,
June 2018 in “Journal of Dermatology” This article updates Japanese guidelines for diagnosing and treating male and female-pattern hair loss, recommending specific drugs and therapies while advising against certain treatments for female-pattern hair loss.
145 citations
,
November 2017 in “Journal of The European Academy of Dermatology and Venereology” This guideline review by the European Dermatology Forum evaluates current treatments for androgenetic alopecia but reports no new research findings, aiming to assist dermatologists in selecting safe and effective therapies.
1 citations
,
January 2016 in “Klinicheskaya dermatologiya i venerologiya”
43 citations
,
August 2014 in “Dermatologic Therapy” This study confirmed that a sulfotransferase enzyme test can effectively rule out 95.9% of nonresponders to 5% topical minoxidil for treating androgenetic alopecia.
20 citations
,
April 2014 in “Dermatologic Therapy” This study reported that sulfotransferase activity in plucked hair follicles can predict treatment response to 5% topical minoxidil in women with androgenetic alopecia with high sensitivity and specificity.
198 citations
,
October 2011 in “Journal der Deutschen Dermatologischen Gesellschaft” This article discusses the development of an evidence-based guideline for treating androgenetic alopecia and reports no new research results.
100 citations
,
June 2011 in “Journal of The American Academy of Dermatology” This study found that a once-daily 5% minoxidil topical foam is as effective as a twice-daily 2% minoxidil topical solution for hair growth in women with androgenetic alopecia, with fewer side effects and greater styling convenience.
52 citations
,
June 2009 in “Current Opinion in Endocrinology, Diabetes and Obesity” This review discusses the pathogenesis and treatment of androgenetic alopecia, highlighting genome associations and newer topical formulations, but reports no new clinical results.
102 citations
,
February 2008 in “The FASEB Journal” This study found that human hair follicles express ATP-sensitive potassium channels, suggesting that minoxidil acts on these channels and that drugs targeting them may treat hair disorders.
142 citations
,
August 2007 in “Journal of The American Academy of Dermatology” This study found that a new 5% minoxidil foam formulation significantly increased hair counts and improved hair loss condition in men with androgenetic alopecia over 16 weeks compared to placebo.
199 citations
,
January 2004 in “The International Journal of Developmental Biology” This review discusses advances in understanding hair and hair follicle structure, gene expression, and molecular signals in hair formation, without reporting new clinical findings.
269 citations
,
August 2002 in “Journal of The American Academy of Dermatology” This study found that 5% topical minoxidil significantly increased hair regrowth and improved psychosocial perceptions of hair loss in men with androgenetic alopecia compared to 2% topical minoxidil and placebo over 48 weeks.
59 citations
,
February 1998 in “Chemico-Biological Interactions” This study found that at least four different human sulfotransferase activities contribute to the sulfation of minoxidil, complicating predictions of individual responses based on ST levels.
309 citations
,
May 1993 in “Journal of The American Academy of Dermatology” This study concluded that horizontal sections of scalp biopsy specimens provide more diagnostic information for male pattern androgenetic alopecia than vertical sections and can predict hair regrowth potential following topical minoxidil therapy.
166 citations
,
November 1990 in “Journal of Investigative Dermatology” Minoxidil sulfate stimulates hair growth.
57 citations
,
July 1987 in “Journal of The American Academy of Dermatology” In this study, minoxidil treatment was associated with an increase in nonvellus scalp hairs, but this effect was not sustained once the treatment was stopped.
55 citations
,
February 1985 in “Archives of Dermatology” In this randomized trial, topical minoxidil treatment resulted in cosmetically acceptable hair growth in 32% of men with hereditary male pattern baldness, with no serious side effects reported.