Applications of Exosomal miRNAs from Mesenchymal Stem Cells as Skin Boosters

    April 2024 in “ Biomolecules ”
    Jianzhong Zheng, Baofeng Yang, S Liu … Miaohua Mo
    Studysummary This review summarizes recent findings on the role of mesenchymal stem cell-derived exosomal microRNAs in skin regeneration and rejuvenation, discussing their potential for treating skin damage and aging, and exploring bioengineering methods to enhance therapeutic effects.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 12

    1. Adipose-Derived Stem Cell Exosomes Antagonize the Inhibitory Effect of Dihydrotestosterone on Hair Follicle Growth by Activating Wnt/Beta-Catenin Pathway Stem Cells International · 2023
    2. Adipose Mesenchymal Stromal Cell-Derived Exosomes Carrying MiR-122-5p Antagonize the Inhibitory Effect of Dihydrotestosterone on Hair Follicles by Targeting the TGF-β1/SMAD3 Signaling Pathway International Journal of Molecular Sciences · 2023
    3. Exosomes Secreted from Adipose-Derived Stem Cells Are a Potential Treatment Agent for Immune-Mediated Alopecia Journal of immunology research · 2022
    4. Dermal Exosomes Containing miR-218-5p Promote Hair Regeneration by Regulating β-Catenin Signaling Science Advances · 2020
    5. Extracellular Vesicles Derived from MSCs Activate Dermal Papilla Cells In Vitro and Promote Hair Follicle Conversion from Telogen to Anagen in Mice Scientific Reports · 2017
    6. Identification of Sirtuin 1 as a Promising Therapeutic Target for Hypertrophic Scars British journal of pharmacology · 2016
    7. Hair Follicle Aging Is Driven by Transepidermal Elimination of Stem Cells via COL17A1 Proteolysis Science · 2016
    8. Hair Follicle Dermal Stem Cells Regenerate the Dermal Sheath, Repopulate the Dermal Papilla, and Modulate Hair Type Developmental Cell · 2014
    9. Androgenetic Alopecia in Males: A Histopathological and Ultrastructural Study Journal of Cosmetic Dermatology · 2009
    10. The Hair Cycle Journal of Cell Science · 2006
    11. The Lack of Significant Changes in Scalp Hair Follicle Density With Advancing Age British Journal of Dermatology · 2005
    12. Hair Cycle and Hair Pigmentation: Dynamic Interactions and Changes Associated with Aging Micron · 2003