Determination of Solute Diffusion Properties in Artificial Sebum

    May 2019 in “ Journal of pharmaceutical sciences ”
    Sen Yang, Lingyi Li, Minsheng Lu … Guoping Lian
    Studysummary This study found that diffusion coefficients of chemicals in artificial sebum are significantly higher than those in stratum corneum lipids, suggesting the hair follicle may significantly contribute to transdermal permeation.
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    Research cited in this study 9

    1. Development of a Two-Dimensional Model for Predicting Transdermal Permeation with the Follicular Pathway: Demonstration with a Caffeine Study Pharmaceutical research · 2017
    2. Contribution of the Hair Follicular Pathway to Total Skin Permeation of Topically Applied and Exposed Chemicals Pharmaceutics · 2016
    3. The In Vitro Use of the Hair Follicle Closure Technique to Study the Follicular and Percutaneous Permeation of Topically Applied Drugs ATLA. Alternatives to laboratory animals · 2012
    4. Human Hair Follicle: Reservoir Function and Selective Targeting British Journal of Dermatology · 2011
    5. Hair Follicles Contribute Significantly to Penetration Through Human Skin Only Shortly After Application as a Solvent Deposited Solid in Humans BJCP. British journal of clinical pharmacology/British journal of clinical pharmacology · 2011
    6. Targeting to the Hair Follicles: Current Status and Potential Journal of dermatological science · 2010
    7. Diffusion Properties of Model Compounds in Artificial Sebum International journal of pharmaceutics · 2007
    8. Transfollicular Drug Delivery: Is It a Reality? International journal of pharmaceutics · 2005
    9. Variations of Hair Follicle Size and Distribution in Different Body Sites Journal of Investigative Dermatology · 2004