Ex Vivo Permeation Parameters and Skin Deposition of Melatonin-Loaded Microemulsion for Treatment of Alopecia

    May 2022 in “ Future Journal of Pharmaceutical Sciences ”
    Asmaa A. Elshall, Amira M. Ghoneim, Heidi M. Abdel-Mageed … Dalia S. Shaker
    Studysummary This study found that a melatonin-loaded microemulsion exhibited controlled release and significant stratum corneum deposition in ex vivo permeation tests, suggesting its potential for further evaluation in treating androgenic alopecia.
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    Research cited in this study 9

    1. Developing Formulations for Drug Follicular Targeting: Nanoemulsions Loaded with Minoxidil and Clove Oil Journal of drug delivery science and technology · 2020
    2. Protective Effects of Melatonin on the Skin: Future Perspectives International Journal of Molecular Sciences · 2019
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    5. Melatonin Vitamin C-Based Nanovesicles for Treatment of Androgenic Alopecia: Design, Characterization and Clinical Appraisal European Journal of Pharmaceutical Sciences · 2018
    6. Minoxidil Skin Delivery from Nanoemulsion Formulations Containing Eucalyptol or Oleic Acid: Enhanced Diffusivity and Follicular Targeting Pharmaceutics · 2018
    7. A Novel Approach for Follicular Delivery of Minoxidil for Treatment of Alopecia Journal of Drug Delivery Science and Technology · 2017
    8. Investigation of Drug Partition Property in Artificial Sebum International Journal of Pharmaceutics · 2007
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