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This study found that a melatonin-loaded microemulsion exhibited controlled release and significant stratum corneum deposition in ex vivo permeation tests, suggesting its potential for further evaluation in treating androgenic alopecia.

This study found that diffusion coefficients of chemicals in artificial sebum are significantly higher than those in stratum corneum lipids, suggesting the hair follicle may significantly contribute to transdermal permeation.

This study reported that nanoemulsions significantly improved the skin permeability of thiocolchicoside compared to its aqueous solution, suggesting they are effective carriers for its transdermal delivery.

This study extended a skin diffusion model to include a porous pathway, effectively explaining the permeability of both polar and lipophilic solutes through the stratum corneum.

This study developed a nanoemulsion of garlic oil and apple cider vinegar loaded with minoxidil to enhance drug permeation through skin, reporting improved ex vivo skin permeation parameters compared to an aqueous dispersion of minoxidil, suggesting potential benefits for treating alopecia areata.