Multipotent Neural Crest Stem Cell-Like Cells from Rat Vibrissa Dermal Papilla Induce Neuronal Differentiation of PC12 Cells

January 2014 in “ BioMed research international ”

Meiying Li, Jin Yu Liu, Wei Wang, Hao Xu, Lifeng Cui, Shuang Liu, Jinying Xu, Shutong Liu, Guangfan Chi, Yulin Li

dermal papilla cells DPCs neural crest stem cell markers neuronal differentiation neurotrophic factors brain-derived neurotrophic factor BDNF glial cell line-derived neurotrophic factor GDNF Nestin P75 hair follicle papilla

Studysummary In this study, dermal papilla cells from rat vibrissae showed potential for treating CNS injuries by secreting neurotrophic factors and promoting neuronal differentiation more effectively than bone marrow mesenchymal stem cells.

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