Expansion of Specialized Epidermis Induced by Hormonal State and Mechanical Strain

    February 2015 in “ Mechanisms of development
    Ho‐Ting Wu, Teresa Easwaran, Carlos D. Offutt … John Foley
    Studysummary This study observed that areola formation in mice requires exposure to pregnancy hormones and mechanical strain, beyond individual stimuli like hormonal milieu or strain alone.
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    Research cited in this study 9

    1. Reprogramming Adult Dermis to a Neonatal State Through Epidermal Activation of Beta-Catenin Development · 2011
    2. Prolactin: An Emerging Force Along the Cutaneous–Endocrine Axis Trends in Endocrinology and Metabolism · 2010
    3. Isolation and Short-Term Culture of Primary Keratinocytes, Hair Follicle Populations, and Dermal Cells from Newborn Mice and Keratinocytes from Adult Mice for In Vitro Analysis and Grafting to Immunodeficient Mice Nature Protocols · 2008
    4. Complex Hair Cycle Domain Patterns and Regenerative Hair Waves in Living Rodents Journal of Investigative Dermatology · 2007
    5. Prolactin Delays Hair Regrowth in Mice Journal of Endocrinology · 2006
    6. Localization of Sex Steroid Receptors in Human Skin PubMed · 2004
    7. Noggin Overexpression Inhibits Eyelid Opening by Altering Epidermal Apoptosis and Differentiation EMBO journal · 2003
    8. Prolactin and Its Receptor Are Expressed in Murine Hair Follicle Epithelium, Show Hair Cycle-Dependent Expression, and Induce Catagen American Journal of Pathology · 2003
    9. Overexpression of Parathyroid Hormone-Related Protein in the Skin of Transgenic Mice Interferes with Hair Follicle Development Proceedings of the National Academy of Sciences · 1994