18 citations
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February 2012 in “Experimental Dermatology” This study found no significant association between selected gene variants and female pattern hair loss, suggesting these genes might not be involved in its development.
9 citations
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March 2020 in “Gene” In this study, certain genetic variations in the ESR1 and ESR2 genes were strongly associated with polycystic ovary syndrome and related metabolic issues in Tunisian women.
May 2026 in “Frontiers in Pharmacology” In this study, DOP treatment improved hair regrowth in androgenetic alopecia by altering local steroid metabolism and follicular morphology.
This study investigated the epigenetic effects of finasteride on reproductive signaling pathways using Sertoli cell models and found that finasteride exposure led to altered epigenetic profiles in multiple genes, including ESR1 and DNMT3A, indicating potential impacts on reproductive-related pathways.
November 2022 in “Scientific Reports” This study found that ESR1 gene polymorphisms may be linked to hormonal imbalances in young women with hyperandrogenism, potentially affecting bone mineral density indirectly.