Topical Minoxidil Rejuvenates Hair Follicles in Men with Androgenetic Alopecia In Vivo

    June 2024 in “ Acta dermato-venereologica ”
    Assaf Zeltzer, Aviad Keren, Ralf Paus, Amos Gilhar
    Studysummary Topical minoxidil effectively stimulates hair growth in men with hair loss.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 16

    1. Androgenetic Alopecia: An Update JAAD International · 2023
    2. MTORC1 Activity Negatively Regulates Human Hair Follicle Growth and Pigmentation EMBO reports · 2023
    3. Observations Suggesting a Contribution of Altered Dermal Papilla Mitochondrial Function to Androgenetic Alopecia Experimental Dermatology · 2022
    4. Effect of Minoxidil Formulations on Human Scalp Skin Xenotransplants on SCID Mice: A Novel Pre-Clinical In Vivo Assay for Androgenetic Alopecia Research Experimental Dermatology · 2022
    5. Peroxisome Proliferator-Activated Receptor-γ Signalling Protects Hair Follicle Stem Cells from Chemotherapy-Induced Apoptosis and Epithelial-Mesenchymal Transition British journal of dermatology/British journal of dermatology, Supplement · 2021
    6. Evidence from a Humanized Mouse Model of Androgenetic Alopecia That Platelet-Rich Plasma Stimulates Hair Regrowth, Hair Shaft Diameter, and Vellus-to-Terminal Hair Reconversion In Vivo British Journal of Dermatology · 2021
    7. Oral Minoxidil Treatment for Hair Loss: A Review of Efficacy and Safety Journal of The American Academy of Dermatology · 2020
    8. Monotherapy for Alopecia Areata: A Systematic Review and Network Meta-Analysis Skin appendage disorders · 2019
    9. Nuclear Factor (Erythroid-Derived 2)-Like-2 Pathway Modulates Substance P–Induced Human Mast Cell Activation and Degranulation in the Hair Follicle The Journal of Allergy and Clinical Immunology · 2018
    10. Minoxidil Induction of VEGF Is Mediated by Inhibition of HIF-Prolyl Hydroxylase International Journal of Molecular Sciences · 2017
    11. Oxidative Stress Management in the Hair Follicle: Could Targeting NRF2 Counter Age-Related Hair Disorders and Beyond? BioEssays · 2017
    12. Oxidative Damage Control in a Human Mini-Organ: Nrf2 Activation Protects Against Oxidative Stress-Induced Hair Growth Inhibition Journal of Investigative Dermatology · 2016
    13. Differential Expression Between Human Dermal Papilla Cells from Balding and Non-Balding Scalps Reveals New Candidate Genes for Androgenetic Alopecia Journal of Investigative Dermatology · 2016
    14. Hair Follicle Aging Is Driven by Transepidermal Elimination of Stem Cells via COL17A1 Proteolysis Science · 2016
    15. Hypothalamic–Pituitary–Thyroid Axis Hormones Stimulate Mitochondrial Function and Biogenesis in Human Hair Follicles Journal of Investigative Dermatology · 2013
    16. Control of Hair Growth and Follicle Size by VEGF-Mediated Angiogenesis Journal of Clinical Investigation · 2001

    Related research 9

    1. Role Of Oral Minoxidil In The Treatment Of Androgenetic Alopecia Cosmoderma · 2024
    2. Oral Minoxidil Treatment for Hair Loss: A Review of Efficacy and Safety Journal of The American Academy of Dermatology · 2020
    3. 5% Minoxidil: Treatment for Female Pattern Hair Loss PubMed · 2015
    4. Minoxidil: Mechanisms of Action on Hair Growth British Journal of Dermatology · 2004
    5. Effects of TNF-Alpha and Minoxidil on Human Hair Growth In Vitro Journal of Clinical Dermatology · 2003
    6. Effect of Minoxidil on Hair Growth in Androgenic Alopecia in Women PubMed · 2002
    7. A Randomized Trial of Minoxidil in Chemotherapy-Induced Alopecia Journal of The American Academy of Dermatology · 1996
    8. The Use of Minoxidil to Prevent Alopecia During Chemotherapy for Gynecologic Malignancies PubMed · 1991
    9. Sulfation of Minoxidil in Keratinocytes and Hair Follicles PubMed · 1989