Deimination and Peptidylarginine Deiminases in Skin Physiology and Diseases

    January 2020 in “ International Journal of Molecular Sciences ”
    Marie‐Claire Méchin, Hidenari Takahara, Michel Simon
    Studysummary This review discusses the role of peptidylarginine deiminases in skin homeostasis and diseases, particularly in keratinocyte differentiation and hair disorders, but presents no new experimental findings.
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    Research cited in this study 9

    1. Variant PADI3 in Central Centrifugal Cicatricial Alopecia The New England Journal of Medicine · 2019
    2. Central Centrifugal Cicatricial Alopecia: New Insights and a Call for Action Journal of Investigative Dermatology Symposium Proceedings · 2017
    3. Arachidonate 12-Lipoxygenase Inhibitors Promote S100A3 Citrullination in Cultured SW480 Cells and Isolated Hair Follicles Biological & pharmaceutical bulletin · 2017
    4. Mutations in Three Genes Encoding Proteins Involved in Hair Shaft Formation Cause Uncombable Hair Syndrome American journal of human genetics · 2016
    5. Evaluation of the Predictive Capacity of DNA Variants Associated with Straight Hair in Europeans Forensic Science International: Genetics · 2015
    6. Common Variants in the Trichohyalin Gene Are Associated with Straight Hair in Europeans American journal of human genetics · 2009
    7. Distinguishing Mouse Strains by Proteomic Analysis of Pelage Hair Journal of Investigative Dermatology · 2009
    8. Peptidylarginine Deiminase Isoforms Are Differentially Expressed in Anagen Hair Follicles and Other Human Skin Appendages Journal of Investigative Dermatology · 2005
    9. Trichohyalin Mechanically Strengthens the Hair Follicle Journal of biological chemistry/˜The œJournal of biological chemistry · 2003