Characterization of the Promoter Regions of Two Sheep Keratin-Associated Protein Genes for Hair Cortex-Specific Expression

April 2016 in “ PloS one ”

Zhichao Zhao, Guangbin Liu, Xinyun Li, Ji Huang, Yujing Xiao, Xiaoyong Du, Mei Yu

keratin-associated protein KRTAP3-3 KRTAP11-1 hair cortex-specific expression promoter regions transgenic mice gene expression hair fiber formation keratin protein hair cortex hair fiber

Studysummary This study found that the promoter region of the sheep KRTAP11-1 gene drives specific transcriptional activity in wool follicles, suggesting it may regulate hair keratinocyte specificity.

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