November 201614
BeauTop in androgenetic alopecia was reported to improve hair growth over placebo in a randomized trial. PRP scalp injections were found to increase hair density and quality, though techniques vary. Tofacitinib in severe alopecia areata produced regrowth in most potential responders, while tofacitinib in adolescents yielded significant regrowth. Valproic acid during radiotherapy delayed hair loss in glioma patients and was associated with improved survival.
- Hair growth effect of traditional Chinese medicine BeauTop on androgenetic alopecia patients: A randomized double-blind placebo-controlled clinical trial In a 40-patient randomized trial, the Chinese herbal formula BeauTop improved hair growth in 52.9% of androgenetic alopecia patients versus 13% on placebo over 6 months.
- Valproic acid reduces hair loss and improves survival in patients receiving temozolomide-based radiation therapy for high-grade glioma In 112 glioma patients, valproic acid during radiotherapy delayed hair loss and was associated with improved survival.
- Platelet-Rich Plasma in Androgenic Alopecia: Indications, Technique, and Potential Benefits A review finds PRP scalp injections increase hair density and quality in androgenic alopecia, but techniques vary and stronger trials are needed.
- Tofacitinib for the treatment of alopecia areata and variants in adolescents In 13 adolescents with alopecia areata, 9 had significant regrowth on tofacitinib with a median 93% SALT score improvement and mild adverse events.
- Tofacitinib for the treatment of severe alopecia areata and variants: A study of 90 patients In 90 patients with severe alopecia areata, 77% of potential responders regrew hair on tofacitinib over 4–18 months, with no serious adverse events.
- Comparison of Saccharina japonica–Undaria pinnatifida Mixture and Minoxidil on Hair Growth Promoting Effect in Mice In mice, a brown seaweed mixture promoted hair growth as effectively as 3% minoxidil over 14 days, via growth-factor and gene changes.
- DNA Damage-Inducible Transcript 4 Is an Innate Surveillant of Hair Follicular Stress in Vitamin D Receptor Knockout Mice and a Regulator of Wound Re-Epithelialization In vitamin D receptor knockout mice, elevated Ddit4 marks an early stress response in degenerating hair follicles and impaired wound healing.
- Dendritic polyglycerol and N-isopropylacrylamide based thermoresponsive nanogels as smart carriers for controlled delivery of drugs through the hair follicle In pig ear skin, 300-500 nm thermoresponsive nanogels penetrated hair follicles deeply and released more drug above their transition temperature.
- Primary cicatricial alopecia A CME review classifies lymphocytic primary cicatricial alopecias including lupus, lichen planopilaris, and frontal fibrosing alopecia.
- Primary cicatricial alopecia A CME review covers remaining primary cicatricial alopecias including pseudopelade, CCCA, folliculitis decalvans, and dissecting cellulitis.
- Induced pluripotent stem cells from human hair follicle keratinocytes as a potential source for <i>in vitro</i> hair follicle cloning Lab work generates induced pluripotent stem cells from human hair follicle keratinocytes as a potential future source for hair follicle cloning.
- A review on laser and light-based therapies for alopecia areata A review finds excimer laser the most studied light-based treatment for alopecia areata, with positive but not yet trial-proven results.
- Megasessions for Robotic Hair Restoration. A report describes robotic megasession hair transplants harvesting 600–800 grafts per hour with high patient satisfaction and rapid healing.
- Hair camouflage: A comprehensive review A review describes wigs, extensions, concealing powders, scalp tattoos, and transplants for camouflaging hair loss, with pros and cons of each.