36 citations
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December 2014 in “F1000 prime reports” The document concludes that Hidradenitis suppurativa is often underdiagnosed, lacks definitive treatment, and requires better awareness and management strategies.
28 citations
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February 2016 in “Journal of biological chemistry/The Journal of biological chemistry” Prostasin has two roles in skin: one for normal skin development without needing activation, and another for proper hair growth that requires activation.
25 citations
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January 2018 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings” Targeted cytokine treatments may help with alopecia areata, but more research is needed.
25 citations
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October 2017 in “Neuropharmacology” Increasing TSPO in the brain reduces anxiety and depression.
24 citations
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March 2009 in “Fertility and sterility” Pioglitazone improved insulin sensitivity and altered cortisol metabolism in PCOS patients.
23 citations
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December 2021 in “Frontiers in Immunology” IL-1 family cytokines are crucial for skin defense and healing, but their imbalance can cause skin diseases.
16 citations
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November 2019 in “Journal of biological chemistry/The Journal of biological chemistry” Mice without certain skin enzymes have faster hair growth and bigger eye glands.
15 citations
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January 2023 in “Antioxidants” Oxidative stress plays a significant role in alopecia areata, and new treatments may include JAK inhibitors and antioxidants.
14 citations
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July 2021 in “Journal of dermatological science” Argan press cake extract might help grow hair and protect hair cells from damage and inflammation.
13 citations
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February 2016 in “Gene” Let-7b helps alpaca hair grow by reducing TGFβR I protein.
11 citations
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January 2020 in “Dermatologica Sinica” Tofacitinib helps regrow hair in severe alopecia patients, but more research is needed.
10 citations
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January 2010 in “International journal of trichology” Keratin-associated proteins are part of the developing hair fiber cuticle.
9 citations
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November 2021 in “Frontiers in Cell and Developmental Biology” PBX1 helps reduce aging and cell death in hair follicle stem cells by decreasing DNA damage, not by improving DNA repair.
9 citations
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March 2018 in “International journal of molecular sciences” Allopregnanolone changes gene expression in glioblastoma cells.
8 citations
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October 2020 in “International journal of biological macromolecules” Certain treatments can increase protein binding to natural hair but are less effective on permed hair.
8 citations
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July 2020 in “Clinical, cosmetic and investigational dermatology” Excessive sun protection might cause frontal fibrosing alopecia by disrupting skin immune balance.
8 citations
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March 2019 in “Nanomedicine” Egyptian researchers are advancing in pharmaceutical nanotechnology, potentially improving health outcomes and the economy.
8 citations
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January 2018 in “Middle East Journal of Digestive Diseases” A man with complete hair loss and ulcerative colitis regrew hair after treatment with azathioprine.
7 citations
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May 2022 in “International Journal of Environmental Research and Public Health” Isotretinoin therapy for acne can cause many reversible side effects, mainly mild skin conditions, and patient understanding of these effects can improve treatment adherence.
6 citations
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January 2016 in “Open journal of regenerative medicine” Keratin treatment reduces astrocyte reactivity and inflammation.
5 citations
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December 2022 in “Toxins” Neurotoxins can affect neurotransmitter release and have potential in treating muscle, pain, and cancer conditions, but more research is needed on how they work.
5 citations
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October 2021 in “Clinical, cosmetic and investigational dermatology” Japanese patients with alopecia areata often have a higher BMI and consume more vitamin C, fruit, and retinol, which may affect their condition's development or severity.
4 citations
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January 2023 in “Skin health and disease” Blocking Janus kinase 1 helps stop inflammation and regrow hair, making it a good treatment for hair loss from alopecia areata.
4 citations
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November 2021 in “Journal of Clinical Medicine” Higher levels of CCL7 are linked to more severe hair loss in alopecia areata patients.
4 citations
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January 2019 in “Dermatology Online Journal” Low-dose naltrexone might be a cheap and effective additional treatment for hair loss with scalp discomfort due to its anti-inflammatory effects and few side effects.
3 citations
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June 2023 in “Journal of cosmetic dermatology” A new drug, abrocitinib, helped a child with severe hair loss regrow hair.
2 citations
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June 2023 in “Indian journal of dermatology, venereology, and leprology” Janus kinase inhibitors can regrow hair in alopecia areata but may cause side effects and hair loss may return if treatment stops.
2 citations
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October 2022 in “Current Allergy and Asthma Reports” Biologic therapies can cause various adverse events, but allergy/immunology clinicians can manage them.
2 citations
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May 2021 in “Asian pacific Journal of Tropical Biomedicine” 2 citations
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December 2020 in “Developmental cell” Chemotherapy drugs can cause abnormal growth and changes in healthy skin and gland cells.