Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This study found that in early retinal neurogenesis in mice, the transcription factor Lhx2 regulates Sonic Hedgehog signaling by controlling expression of pathway genes like the co-receptors Gas1 and Cdon.

Lichen planus may be associated with a higher risk of metabolic syndrome.

During LIFEHOUSE, researchers documented distinct patterns of physical exam findings and biomarker abnormalities in 369 adult employees, which may aid clinicians in recognizing wellness challenges and preventing chronic diseases associated with aging.

This article discusses the potential misdiagnosis issues in cutaneous manifestations of lupus erythematosus and reports no new research findings.

This review discusses valproic acid as a common antiseizure medication associated with alopecia and highlights the need for its inclusion in relevant medical guides, without presenting new clinical findings.

This study conducted at a Moroccan tertiary dermatology center describes the characteristics of pediatric lichen, highlighting that dermoscopy can improve diagnostic accuracy by identifying distinct patterns across clinical variants, with lichen sclerosus being the most frequent subtype among the children studied.

This study found that biallelic LSS mutations lead to congenital hypotrichosis and cataracts, with each tissue-specific loss of function observed in mouse models.

This study identified biallelic variants in the LSS gene as a possible genetic cause of palmoplantar keratoderma-congenital alopecia syndrome type 2, highlighting the role of cholesterol synthesis in skin cornification.

This study found that systemic lupus erythematosus was diagnosed earlier in males than females, with a notable delay in diagnosis for females often due to confounding symptom overlaps with other conditions.

This study observed variable therapeutic responses in dogs with Alopecia X, with some showing complete hair regrowth while others did not, following similar treatments including orchiectomy and supplementation.

This case report describes a patient with untreated lepromatous leprosy developing Lucio's phenomenon, highlighting difficulties in distinguishing it from erythema nodosum leprosum with vasculonecrotic lesions.

This study explored using large language models to automatically identify monkeypox cases from electronic medical records, finding that models based on DeepSeek features performed better than traditional methods, with logistic regression showing high accuracy in detecting key symptoms like fever and rash.

This study reports a rare case of two siblings with lipoedematous scalp, suggesting a possible genetic link that warrants further investigation.

The researchers reported that Lrig1 overexpression was observed in 100% of sebaceous carcinoma cases, suggesting it may serve as a potential marker for poorly differentiated sebaceous carcinoma.

This article discusses revised SLE classification criteria by the SLICC and reports no new research results.

This study demonstrated that a wearable bioelectronic patch with combined therapy significantly accelerated chronic wound healing in a rodent model by monitoring and treating wounds noninvasively.

In this study, the researchers developed a living microecological hydrogel containing Chlorella and Bacillus subtilis that showed potential in promoting the healing of infected diabetic wounds by providing continuous oxygen delivery and anti-infective properties.

This study found that absence of the vitamin D receptor in keratinocytes impairs canonical Wnt signaling and leads to alopecia due to defects in keratinocyte stem cells.

This study identified that bone marrow-derived CD34⁺ cells act as fibroblast progenitors to enhance tissue regeneration in ischemic limbs by promoting angiogenesis through interactions with macrophages.

This study found that in mice, low-dose irradiation causes stem cells in hair follicles to undergo chromatin alterations, which may eventually lead to long-term functional loss in tissues or organs.

This study found that the ROCK inhibitor Y-27632 maintains self-renewal and stemness of hair follicle stem cells in vitro, supporting their potential for tissue engineering applications.

This study found that serum APN levels were inversely related to insulin resistance in women with PCOS, suggesting that APN could serve as a clinical marker for insulin resistance in this population.

The researchers reported that targeting glycoprotein 130's signaling site in animal models promoted tissue regeneration and reduced osteoarthritis progression through anti-inflammatory and protective effects.

This study found that bacterially induced metabolic changes in stem cells can enhance skin and hair follicle regeneration in both mice and humans, suggesting potential strategies for improving recovery after injury.

This review discusses the role of the MC1R gene in human pigmentation and its genetic variants, reporting no new results; the authors highlight its forensic applications for phenotypic prediction.

This review highlights the potential of adipose-derived mesenchymal stem cells as a cost-effective solution for tissue restoration and regeneration in ophthalmic and oculoplastic surgeries, addressing unmet needs in reconstructive procedures.

This review discusses the modern production methods, mechanisms of action, and various uses of platelet-rich plasma in medicine, highlighting promising applications but noting the need for more high-quality research.

This retrospective cohort study reported that oral tofacitinib was effective in treating alopecia areata, with 83.2% of patients showing improvement and 16.0% achieving complete remission. Earlier intervention and previous hair regrowth were linked to better outcomes, and no severe adverse events were observed.

This review suggests that metformin, known for its antidiabetic uses, may benefit chronic inflammatory skin diseases like acne vulgaris, hidradenitis suppurativa, and rosacea due to its multiple therapeutic properties, although more research is needed to confirm its efficacy in dermatology.

This study found that platelet-rich plasma microneedles promoted hair regrowth in mice by facilitating angiogenesis and cell proliferation, showing promise for a minimally invasive hair regeneration treatment.