Is Lichen Planus a Marker for Dyslipidemia and Metabolic Syndrome?

    April 2016 in “ Journal of The American Academy of Dermatology ”
    Image of study
    TLDR Lichen planus may be associated with a higher risk of metabolic syndrome.
    The study from 2016 investigated whether lichen planus (LP), an autoimmune inflammatory disorder, could be a marker for dyslipidemia and metabolic syndrome (MetS). The case-control study included 39 patients with biopsy-proven LP and 78 age- and sex-matched healthy controls. The participants were evaluated for MetS using the International Diabetes Federation criteria and for dyslipidemia using the National Cholesterol Education Program-Third Adult Treatment Panel definition. The results showed that 59% of LP patients met the criteria for MetS compared to 32% of controls, which was a significant difference (OR=3.047, P=.006). Dyslipidemia was found in 35.9% of LP cases versus 21.8% of controls, although this difference was not statistically significant (P=0.108). There was no significant difference in inflammatory markers between the two groups. The study concluded that there is a higher prevalence of MetS in patients with LP compared to healthy controls, suggesting an association between LP and MetS as well as dyslipidemia. The authors recommend screening for MetS in patients with LP due to potential long-term complications. No commercial support was identified for this study.
    Discuss this study in the Community →

    Related Community Posts Join

    6 / 57 results
      If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      in Research  830 upvotes 7 months ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community Duta 2,5mg/day - No Progress - 28M

      in Update  3 upvotes 2 days ago
      A 28-year-old is experiencing hair loss despite using treatments like oral minoxidil, finasteride, and high-dose dutasteride (2.5 mg). They suspect lichen planus might be contributing to the issue and plan to continue treatment while monitoring progress.

      community I've tried everything and my hair is still thinning

      in Chat  6 upvotes 1 year ago
      The user has tried finasteride, oral minoxidil, iron supplements, vitamin D, and vitamin B12, but their hair is still thinning after 5 years. Another user suggested trying dutasteride.

      community Clascoterone (Winlevi) Update for Canada

      in Treatment  16 upvotes 2 years ago
      Clascoterone cream was submitted for review to Health Canada in August 2022, with hopes of approval within 3-6 months. It may potentially enhance finasteride's effects for hair loss treatment.

      community He used Dutasteride for 20 years. Interview

      in Treatment  112 upvotes 4 months ago
      Dutasteride has been used for 20 years with some hair thickness improvement but no dramatic regrowth. The user also experimented with minoxidil, tretinoin, and peptides like BPC 157 for potential benefits in hair density and quality.

      community Pili migrans? Lichen something? Seb derm?

      in Female  19 upvotes 1 week ago
      The conversation is about a female experiencing hair loss and seeking advice on why it's difficult to regrow hair. Specific treatments like Minoxidil, finasteride, or RU58841 are not mentioned.

    Related Research

    1 / 1 results