Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This study found that in a mouse model of Focal Dermal Hypoplasia, treatment with lithium carbonate improved skin disease symptoms compared to controls, though disease severity varied and posed interpretation challenges.

This case report describes a father with HOXC13-associated pure hair-nail ectodermal dysplasia, presenting with severe nail dystrophy affecting all digits and notable hypotrichosis or complete alopecia.

This paper evaluates the therapeutic response of androgenetic alopecia to topical application of specific compounds using digital drug delivery but reports no new clinical results.

This study found significant differences in mRNA and miRNA expression between yak dermal papilla cells and epidermal hair matrix cells, suggesting important roles for these molecules in hair follicle development.

This study found that postnatal treatment with recombinant EDA normalized adult teeth, improved sweating, and restored normal lacrimation in dogs with XLHED, suggesting its potential as a treatment for the condition.

This report presents a case of IFAP syndrome with the typical symptoms of alopecia universalis, severe photophobia, and follicular ichthyosis, but provides no additional clinical findings or conclusions.

This study concluded that the Chinese herbal medicine Xianhuayin effectively reversed DMBA-induced premalignant lesions in the buccal pouch of golden hamsters.

This study found that epigallocatechin-3-gallate (EGCG) may reduce paclitaxel-induced apoptosis in human dermal papilla cells by regulating microRNA expression related to apoptosis and cell proliferation.

This study found that the alcoholic extract of Eclipta alba exhibited dose-dependent antianaphylactic effects in animal models, possibly due to membrane stabilization and reduced histamine release.

This study revealed gene expression patterns in yak hair follicles during different growth phases, enhancing the understanding of cell fate specialization and providing insights for yak villus development.

This quiz presents educational questions about alopecia areata, including its diagnosis and underlying mechanisms, but reports no new clinical outcomes.

In this study, researchers found that overexpression of CRABP2 enhanced the proliferation of dermal papilla cells in Hu sheep through activation of the Wnt/β-catenin pathway, even when the pathway was inhibited.

This study found that snoring during sleep, frequent consumption of bacon and preserved meats, and drinking unboiled water, along with older age and suboptimal health, were associated with a higher likelihood of female androgenetic alopecia in a community-based sample of women in China.

This study reports a case of a child with congenital skin fragility, alopecia, and cardiomyopathy due to compound heterozygous mutations in the DSP gene causing desmoplakin deficiency.

This study found that the Polycomb Repressive Complex 2, particularly its component Ezh2, is crucial in regulating dermal fibroblast differentiation and epidermal keratinocyte proliferation during murine skin development.

Tanshinone IIA helps protect tissue from low oxygen damage by activating certain cell pathways.

This study found that cPPARγ and dnPPARγ isoforms are differentially expressed in healthy human skin, suggesting that PPARγ modulators may have compartment-specific effects depending on isoform presence.

This study found that in Pomeranians with Alopecia X, key genes in the Wnt and Shh signaling pathways and stem cell markers are downregulated, which may explain the absence of anagen hair follicles.

Ozenoxacin 1% cream is an effective and safe treatment for impetigo in children and adults.

This report describes a neurometabolic disorder linked to gain-of-function variants in the ODC1 gene, characterized by developmental delay, ectodermal abnormalities, and notable facial and neuroimaging features.

This study found that Zhuangyao Jianshen pill significantly improved prostate health in testosterone-induced benign prostatic hyperplasia in castrated rats by modulating sex hormones and reducing inflammation and oxidative stress.

The researchers reported that protocatechuic acid reduced melanin synthesis and enhanced antioxidant activity in cultured human hair follicle melanocytes, indicating potential for skin whitening applications.

In this report, a unique female presentation of IFAP syndrome is described, featuring musculoskeletal contractures but no photophobia, highlighting the importance of early detection and multidisciplinary care to improve outcomes and prevent disability.

This article introduces the concept of organ size control in regeneration, regulated by the Hippo signaling pathway, but reports no new experimental results.

This study found that TAp63 and ΔNp63 isoforms in the p63 family interact with different transcription factors to regulate distinct transcriptional programs, affecting various biological functions like metabolic pathways, oxidative stress response, and epithelial morphogenesis in mouse epidermal cells.

Women's hair has more sulfur, and black hair has more calcium than white hair.

This study found that the RNA helicase DDX6 is essential for maintaining self-renewal in epidermal progenitor cells by promoting the translation of proliferation regulators and degrading differentiation-inducing mRNAs.

In a reported case, the use of ZD1839 (Iressa), an EGFR tyrosine kinase inhibitor, resulted in hair changes and acneiform eruptions as cutaneous side effects.

This study reported that early-onset androgenetic alopecia primarily affects Chinese males aged 21–30, with a high likelihood of paternal inheritance.

This study found that the topical application of DA-OTC-002, a combination of synephrine and tyramine hydrochloride, significantly reduced immediate hair shedding in women by 62.5% compared to a placebo, without any observed adverse effects.