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Increased cell death and reduced cell growth in hair follicles contribute to baldness.

A 27-year-old with APS-1 showed improvement in symptoms after treatment.

A new gene variant causes glucocorticoid resistance in a mother and son.

People with Down syndrome have higher rates of certain immune-related conditions and need special medical attention.

Certain changes in the SHBG gene may increase the risk of PCOS in Iraqi women.

Two siblings had a rare immune disorder caused by a FOXN1 gene mutation.

A 10-year-old boy with abnormal genital development had surgery and tests to find the cause and plan treatment.

The document is a detailed medical reference on skin and genetic disorders.

A mother and daughter have a rare genetic hair loss disorder with no effective treatment.

The gene Foxn1 is important for hair growth, and understanding it may lead to new alopecia treatments.

Cancer treatments targeting specific cells often cause skin, hair, and nail problems, affecting patients' lives and requiring careful management.

A new TP63 mutation was found in a baby with EEC syndrome, showing the need for TREC testing to check for immune issues.

Certain gene mutations can weaken the skin barrier and, when combined with environmental factors, lead to eczema and severe itching.

The document concludes that early diagnosis and treatment of PCOS in teenagers is important for managing symptoms and preventing long-term health problems.

PCOS may have evolved as an advantage in past environments with food scarcity.

Terbinafine is more effective than itraconazole for toenail fungus, especially in older patients, and debridement improves its effectiveness.

The vitamin D receptor is crucial for bone health and affects various body systems, with mutations potentially leading to disease.

Vitiligo is a skin condition causing white spots, more common in women, often starts before age 20, and can affect mental health.

Fat-related cells are important for initiating hair growth.

Half of people with Alopecia Areata may see hair regrowth within a year without treatment, but recovery is unpredictable.

Childhood obesity is rising globally due to various factors, and early prevention and healthy lifestyle changes are crucial.

Certain proteins, Lgr5 and Lgr6, are important markers of adult stem cells and are involved in tissue repair and cancer development.

The Rotterdam Study aims to understand disease causes in the elderly and has found new risk factors and genetic influences on various conditions.

Mutations in the SRD5A3 gene cause a new type of glycosylation disorder by blocking the production of a molecule necessary for protein glycosylation.

The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.

The document concludes that the fast-growing direct-to-consumer genetic testing market lacks sufficient regulation, posing risks to consumers due to questionable test quality and accuracy.

Msx and Dlx genes are crucial for development, controlling cell behaviors like growth and differentiation through their roles as gene regulators.

Keratins are crucial for cell structure, growth, and disease risk.

WNT10A mutations often cause ectodermal dysplasias, with males showing more tooth issues than females.

Blocking COX, especially COX-2, in the skin can reduce inflammation and pain and may help prevent skin cancer.