April 2025 in “Antioxidants” In this study, the researchers found that the water-soluble fraction of Rhus semialata gall extract and its component Penta-O-Galloyl-β-D-Glucose promoted hair growth in human dermal papilla cells, and clinical trials supported these findings, showing improved hair density and appearance compared to placebo.
July 2024 in “Journal of Investigative Dermatology” JW0061 may be a new treatment for hair loss by promoting hair growth through WNT signaling.
76 citations
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January 1998 in “Mammalian Genome”
4 citations
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May 2020 in “Cureus” This case report describes an adult male from India with Werner's syndrome due to a novel homozygous mutation in the WRN gene, characterized by several premature aging symptoms.
April 2024 in “bioRxiv (Cold Spring Harbor Laboratory)” In this study, researchers identified a gene regulatory network in Arabidopsis that controls root hair growth under low-temperature conditions, revealing specific transcription factors and downstream targets that contribute to this growth response despite overall plant development being halted.
August 2008 in “European Neuropsychopharmacology” RY-023, a specific drug, can improve early stage memory learning without affecting general activity in rats, but it's less effective for later learning stages and doesn't impact memory recall.
6 citations
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October 2020 in “Endocrine journal” This case report identifies two specific mutations in the WRN gene in a 40-year-old female with Werner syndrome, highlighting the need for awareness of its early manifestations and treatment options.
October 2024 in “Journal of the Endocrine Society” This case report highlights that a patient with resistance to thyroid hormone was misdiagnosed as having Graves’ disease, leading to unnecessary radioactive iodine treatment.
April 2019 in “Journal of Investigative Dermatology” This study identifies a mechanism where dsRNA activates TLR3 to induce RA production, promoting hair follicle regeneration in mice and suggesting a potential role in human tissue regeneration.
210 citations
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February 2008 in “Nature genetics” This study found mutations in the P2RY5 gene that are linked to autosomal recessive woolly hair in Pakistani families, implicating it in hair texture determination.
11 citations
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December 2024 in “Wound Repair and Regeneration” In this study, researchers created the WRAHPS Guidelines to standardize the reporting of preclinical wound healing studies, aiming to improve transparency, enable comparative analysis, and support the development of human clinical trials for wound healing disorders.
January 2019 in “Industrial Law Journal” This article reviews two new legislative measures affecting domiciliary care workers in Wales and reports no new research results; it highlights implications for labor law and devolution debates.
66 citations
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May 2002 in “The Plant Journal” This study identified a mutant in Arabidopsis with shorter root hairs due to early growth cessation, implicating the IRE gene in regulating root hair growth duration.
This study found that elastin-like recombinamer (ELR) wound dressings promote tissue regeneration and stability without rejection in ex vivo and in vivo models, indicating potential for hard-to-heal wound treatment.
April 2025 in “Drug Design Development and Therapy” This study observed that the herbal extract WJWE promoted hair growth and protected hair follicle cells in a DHT-induced murine model of androgenetic alopecia, potentially by engaging the SIRT1/JNK/p38 MAPK and Wnt5A/β-Catenin signaling pathways.
58 citations
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February 2013 in “Journal of Biological Chemistry” This study identifies specific molecular components involved in the intracellular trafficking of LGR5, revealing mechanisms that differ from typical GPCR recycling processes.
October 2023 in “Clinical, Cosmetic and Investigational Dermatology” This study found that supplemented Erzhi Wan enhanced hair regrowth in a mouse model of androgenetic alopecia and identified potential mechanisms through oxidative stress and signaling pathways.
45 citations
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January 2010 in “Journal of Veterinary Medical Science” This study identified a mutation in the keratin 71 gene that causes curly hair in certain rats, advancing our understanding of hair formation.
January 2008 in “US endocrinology” This paper describes the hGRα gene structure and its expression, focusing on the functional properties of the longest GRα isoform, but reports no new results.
5 citations
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January 2012 in “Indian Journal of Dermatology Venereology and Leprology” Werner's syndrome causes early aging and increases cancer risk, requiring early diagnosis and symptom management.
5 citations
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December 2023 in “Current Biology” A feedback loop between LRH and RSL4 controls root hair growth in Arabidopsis.
September 2023 in “Plant journal” This study showed that the zinc finger protein GIS3 is important for root hair growth in Arabidopsis by regulating RHD2 and RHD4 genes, with application of ethylene and cytokinin helping restore root hair presence in mutated variants.
10 citations
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November 2015 in “Experimental Dermatology” The study observed that mRAGE expression is prevalent in keratinocytes of the healthy human epidermis and may regulate inflammation and apoptosis to maintain skin homeostasis rather than responding to aging processes.
9 citations
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October 2017 in “Frontiers in plant science” This study found that the peach gene CTG134 mediates auxin-ethylene crosstalk, affecting root hair growth and hormone-regulated processes in plants.
June 2023 in “British Journal of Dermatology” This case study confirmed a diagnosis of Werner syndrome in a 27-year-old woman through genetic testing, highlighting the condition's characteristics and the importance of multidisciplinary management.
1 citations
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September 2011 in “Journal of the American Geriatrics Society” This article presents a case of Werner syndrome complicated by idiopathic membranous nephropathy, suggesting a possible but unproven genetic link between the two conditions.
April 2018 in “Journal of Investigative Dermatology” This study found that high skin expression of amphiregulin in acute graft-versus-host disease was associated with severe disease grade, poor overall survival, and increased non-relapse mortality.
212 citations
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May 2012 in “Genes & Development” This study identified a set of wound-induced genes in planarians that play a role in regeneration initiation, with some genes specifically activating within regenerative cells called neoblasts.
4 citations
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February 2022 in “International Journal of Cosmetic Science” This study found that watercress extract may help treat hair loss by increasing RSPO1 secretion and decreasing DKK1 secretion, improving hair thickness and density in clinical trials.
January 2026 in “Industrial Crops and Products” In this study, oral administration of ginsenoside Rf from Panax ginseng promoted hair regrowth and increased hair thickness in a mouse model of androgenetic alopecia by enhancing androgen receptor degradation, highlighting its potential for cosmetic and functional food applications.