March 2024 in “International journal of pharmaceutical and bio-medical science (Print)” This review examines Angelica sinensis and Chinese arborvitae, highlighting their historical and contemporary use in traditional Chinese medicine and pharmacology. It emphasizes the need for more comprehensive scientific assessments to fully explore their therapeutic potential.
In this study, a polyphenol and biotin supplement improved skin roughness and significantly reduced hair shedding, but did not demonstrate clear superiority over placebo in overall skin outcomes.
10 citations
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January 2020 in “Biomedicine & Pharmacotherapy” This study found that XiaoZhenFang (XZF) reduced skin toxicities caused by Erlotinib in a mouse model, likely through mechanisms involving inflammation and EGFR-related pathways.
4 citations
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January 2010 in “Animal” Improving knowledge and practices in animal fibre production is crucial to meet market demands and potentially revive natural fibres.
4 citations
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May 2020 in “Annals of palliative medicine” In this clinical study, plum blossom needle acupuncture and qi-invigorating therapy were reported to be more effective than conventional Western medicine for treating seborrheic alopecia, as they improved hormone levels, reduced hair loss, and stimulated hair growth among the 87 patients observed.
January 2023 in “International journal of advances in scientific research and engineering” This review explores the potential of anthocyanins, a type of flavonoid with antioxidant and anticancer properties, to reduce colorectal cancer risk without side effects, focusing on their impact on molecular mechanisms, cancer cell proliferation, and apoptosis.
9 citations
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May 2021 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology” This study suggests that topical minoxidil may be a promising treatment for isolated autosomal recessive woolly hair due to LIPH mutations, although effective treatments are not yet established.
This study found significant differences in cashmere fiber diameters between two groups of cashmere goats and identified 211 genes and 50 metabolites related to hair follicle growth and cellular functions, suggesting potential pathways to improve cashmere quality.
September 2018 in “Reactions Weekly” Two women had skin reactions from a hair loss treatment and got better after stopping use.
34 citations
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September 2007 in “Experimental Dermatology” This study found that the outer protein layer of Merino wool is rich in sulfur-containing proteins similar to those found in both sheep wool and human hair.
91 citations
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April 2011 in “Journal of Ethnopharmacology” This study found that Polygonum multiflorum extract may promote hair growth by inducing the anagen phase in the resting hair follicles of mice.
September 2021 in “Zenodo (CERN European Organization for Nuclear Research)” This article discusses the global interest and market presence of biotin-based supplements like Folexin for preventing alopecia, but it reports no new research findings.
This study demonstrated that the differential wetting characterization (DWC) method can effectively differentiate changes in the wetting properties of hair fibers after chemical or physical treatment.
1 citations
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January 2014 This study found that Crataegus pinnatifida extract promoted hair growth in mice by inducing the anagen phase, potentially through activating signaling pathways that enhance cell survival.
November 2025 in “The Journal of Immunology” In a murine model of alopecia areata, this study observed that the IL-2 fusion protein HCW9302 helped prevent disease development by expanding regulatory T cells and reducing disease-causing effector T cell infiltrates, suggesting potential for using IL-2 fusion proteins in alopecia areata treatment.
May 2025 in “Experimental Dermatology” In this study, researchers developed a novel genetic tool using Wif1-CreER knock-in mice for precise labeling and manipulation of dermal papilla cells, which could enhance understanding of hair biology and aid in developing targeted therapies for hair-related disorders.
3 citations
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February 2019 in “Animal biotechnology” In this study, the PLP2 gene was found to promote secondary hair follicle development in Liaoning cashmere goats, with its expression negatively regulated by melatonin and potentially affecting follicle development via the BMP pathway.
2 citations
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May 2023 in “Journal of Advanced Research” In this study, researchers identified two genetic mutations associated with producing finer and denser wool in fine-wool sheep, involving the genes KRT74 and EDAR, which may guide future breeding efforts to enhance wool quality.
2 citations
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June 2024 in “Frontiers in Plant Science” This study found that RALF peptides, through liquid-liquid phase separation, form condensates with pectin and other proteins, playing a pivotal role in plant development and stress response regulation.
January 2022 in “Lumbung Farmasi: Jurnal Ilmu Kefarmasian/Lumbung Farmasi” In this experimental study, researchers found that a hair tonic combining celery leaf extract and honey, specifically Formula B, showed the highest potential for promoting hair growth in rabbits, with outcomes comparable to a minoxidil control.
25 citations
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January 1958 in “Elsevier eBooks”
6 citations
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January 2016 in “Evidence-based Complementary and Alternative Medicine” In this study, fermented herbal extracts promoted hair growth and activated Wnt signaling more effectively than nonfermented extracts in mice, suggesting potential benefits for hair regrowth.
136 citations
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April 2013 in “Clinical Cancer Research” The study found that IPI-926 was well tolerated up to 160 mg once daily for 28-day cycles and showed activity as a single-agent treatment in Hedgehog pathway inhibitor-naïve patients with basal cell carcinoma.
19 citations
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April 2020 in “Oxidative Medicine and Cellular Longevity” This study provides evidence that Fernblock® upregulates antioxidant pathways in cultured keratinocytes, potentially protecting against damage from fine pollutant particles.
26 citations
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October 2018 in “International journal of osteoarchaeology” This study found evidence of fern consumption in the medieval population of the Balearic Islands by identifying fern sporangium annuli in dental calculus, suggesting potential medicinal usage.
19 citations
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April 2015 in “International Journal of Molecular Sciences” This study identified distinct gene expression patterns in wool follicle bulbs that may play important roles in wool follicle cycling and regeneration in sheep.
11 citations
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December 2020 in “G3 Genes Genomes Genetics” This study confirmed that chi-miR-130b-3p regulates the proliferation of epithelial cells and dermal fibroblasts by targeting the WNT10A gene, which may help maintain hair follicle structure.
April 2018 in “The journal of investigative dermatology/Journal of investigative dermatology” This study observed that Ginseng and Albizia extracts, when used together, protected human dermal papilla cells from oxidative stress-induced senescence, and inhibited genes that suppress hair growth, indicating their potential in preventing age-related hair density reduction.
9 citations
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November 2017 in “Frontiers in Pharmacology” This study found that Shengfu oil may enhance wound healing in scalded rabbit skin by regulating proteins β-catenin, Dlk1, and COX-2, due to its anti-inflammatory, analgesic, and antimicrobial properties.