Shengfu Oil Enhances the Healing of Full-Thickness Scalded Skin Accompanying the Differential Regulation of β-Catenin, Dlk1, and COX-2

    November 2017 in “ Frontiers in Pharmacology ”
    Mantang Chen, Yanjing Yang, Yu-Sang Li, Xiaojun Li, Wei Kevin Zhang, Jinping Wang, Xu Wang, Guihua Tian, He‐Bin Tang
    TLDR Shengfu oil speeds up wound healing by reducing inflammation and promoting tissue repair.
    Shengfu oil, a traditional Chinese medicinal compound, was shown to enhance the healing of full-thickness scalded skin in a study involving 36 rabbits. The oil demonstrated significant anti-inflammatory, analgesic, and antimicrobial properties, leading to less swelling, smoother eschars, and faster healing compared to sesame oil or mupirocin. By the 43rd day, wounds treated with Shengfu oil were smooth, soft, and exhibited new hair growth, unlike the other treatments. The study indicated that Shengfu oil promoted scarless healing and hair regrowth by regulating proteins β-catenin, Dlk1, and COX-2, suggesting it could be an effective and economical alternative for wound treatment.
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