This study investigated the "simmer pus and grow meat" method's effect on chronic wound healing in rats, focusing on the bFGF/Wnt/β-Catenin signaling pathway. Using 100 SPF rats, researchers divided them into four groups: blank, model, experimental (treated with purple and white ointment), and wet burn ointment. Results showed that the experimental and positive control groups had higher wound healing rates compared to the model group. The study found that Zibai ointment enhances wound healing by increasing the expression of bFGF, β-Catenin, and other proteins involved in the signaling pathway, suggesting its potential effectiveness in promoting chronic wound healing.
136 citations
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May 2019 in “Cells” Stem cell therapy, particularly using certain types of cells, shows promise for treating hair loss by stimulating hair growth and development, but more extensive trials are needed to confirm these findings.
140 citations
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November 2018 in “Pharmacology & Therapeutics” Using drugs to activate the Wnt/β-catenin pathway has potential for treating diseases but also presents challenges.
132 citations
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June 2016 in “Cell and Tissue Research” The right cells and signals can potentially lead to scarless wound healing, with a mix of natural and external wound healing controllers possibly being the best way to achieve this.
29 citations
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January 2021 in “Journal of nanobiotechnology” Tiny particles from brain cells help hair grow by targeting a specific hair growth pathway.
March 2024 in “Biomedicines” Mesenchymal stem cells show promise for effective skin repair and regeneration.
August 2020 in “Research Square (Research Square)” Neural progenitor cell-derived nanovesicles help hair growth by activating a key signaling pathway.
61 citations
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April 2023 in “Bioactive Materials” Microneedles are effective for painless drug delivery and promoting wound healing and tissue regeneration.
