TLDR Sanhuang Fukang oil helps heal radiation skin injuries by reducing inflammation and cell death.
The study found that Sanhuang Fukang oil (SHFKO) effectively treats radiodermatitis by promoting faster healing of radiation-induced skin injuries. It works through multiple mechanisms, including inhibiting apoptosis, reducing pro-inflammatory mediators, inhibiting the MAPK/PI3K-AKT pathway, and restoring ROS homeostasis. These results indicate that SHFKO could be a promising candidate for clinical development in treating radiation dermatitis, providing a multi-target therapeutic approach that differs from conventional methods.
1 citations
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March 2024 in “International journal of molecular sciences” Radiation therapy damages skin structure and immune function, causing inflammation and potential hair loss.
9 citations
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June 2023 in “Cells” Certain natural and synthetic compounds may help treat inflammatory skin diseases by targeting a specific signaling pathway.
16 citations
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February 2019 in “Journal of Cellular and Molecular Medicine” Researchers created a rat model to study skin damage caused by radiation, which could help develop new treatments.
117 citations
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March 2017 in “Nature Communications” Macrophages help regrow hair by activating stem cells using AKT/β-catenin and TNF.
610 citations
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April 2014 in “Nature Reviews Immunology” The document concludes that understanding how the skin's immune system and inflammation work is complex and requires more research to improve treatments for skin diseases.
1 citations
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January 2019 in “British Poultry Science” VEGF and VEGFR-2 genes influence feather maturity, and specific genetic markers can improve chicken breeding.
9 citations
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November 2017 in “Frontiers in Pharmacology” Shengfu oil speeds up wound healing by reducing inflammation and promoting tissue repair.
