January 2024 in “Journal of Cosmetics, Dermatological Sciences and Applications” This study found that electronically-operated pneumatic injections for administering a peptide-hyaluronic acid combination were well tolerated and led to significant improvement in hair density and thickness for men with androgenic alopecia over six months, though the exact mechanism remains uncertain.
July 2023 in “Journal of the European Academy of Dermatology and Venereology” In a Phase II trial, Cox and colleagues reported that anti-IL17A therapy was well tolerated and led to a 64% reduction in wound size for venous leg ulcers unresponsive to standard treatments, although further validation in a larger trial is needed.
April 2023 in “Dermatology practical & conceptual” This study observed that a tacrolimus solution (0.1%) applied to the scalp was effective and well-tolerated for treating inflammatory scalp conditions, with 72.7% of patients showing an excellent response after 2 months of treatment, which persisted after 6 months.
November 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that early pigment cell markers Sox10 and c-KIT, as well as DCT/TRP-2, were detectable in melanogenically-active melanocytes of the anagen bulb in human hair follicles.
November 2021 in “CRC Press eBooks” This review discusses the genetic and metabolic factors influencing hair pigmentation, as well as conditions leading to hypo- or depigmented hair, and reports no new experimental findings.
July 2021 in “Journal of dermatology & dermatologic surgery” In this study, two patients with severe alopecia areata who did not respond well to oral tofacitinib showed more than 50% hair regrowth after a single dose of intramuscular triamcinolone acetonide.
September 2020 in “Scientific periodicals of Ukraine” This study found that the combination therapy of Flosin and Prostamol Uno over nine years was well tolerated and equally effective in managing benign prostatic hyperplasia symptoms as the combination of doxazosin and finasteride, with fewer adverse events reported.
June 2020 in “Jurnal Penyakit Dalam Indonesia” This case study highlights that primary biliary cholangitis in a patient with systemic lupus erythematosus can respond well to ursodeoxycholic acid therapy, and anti-DFS70 findings may require further evaluation for other nonsystemic autoimmune conditions.
This study reported that various medications, including known agents like finasteride and testosterone as well as unexpected ones like certain psychotropics and statins, are linked to male infertility cases in the Vigibase database.
November 2017 in “Expert review of quality of life in cancer care” This review observed that recent trials in the United States reported scalp cooling devices being effective and well tolerated for many patients in preventing chemotherapy-induced alopecia, with hair retention rates varying based on specific chemotherapy drugs and regimens.
June 2017 in “Journal of the American Academy of Dermatology” In this retrospective study, tofacitinib was found to be effective and well-tolerated for treating severe alopecia areata, with 77% of patients achieving a clinical response over 4-20 months, though results were more favorable for patients with less extensive hair loss.
This study found that platelet-rich plasma significantly enhanced the viability, as well as the expression of alkaline phosphatase and versican, in human hair dermal papilla cells compared to controls.
This chapter discusses the chemical changes and possible heat-induced hair damage from thermal straightening, as well as controversies surrounding the safety of keratin straightening treatments, but it reports no new clinical results.
January 2016 in “Indian Journal of Paediatric Dermatology” This study found that a combination treatment using oral and topical steroids with topical minoxidil was well-tolerated in children with severe recalcitrant alopecia areata, showing good responses except in alopecia universalis cases.
This study found that Nourkrin significantly improved hair growth in individuals with hair loss and was well-tolerated, suggesting it may be a viable alternative to pharmacotherapy for androgenetic alopecia.
This review explains that linoleic acid deficiency can lead to skin and growth issues but notes that such deficiencies are rare in well-nourished Western populations; it reports no new clinical findings.
July 2011 in “Springer eBooks” This review discusses both conventional and new pharmaceutical treatments for hair loss, as well as various natural and herbal remedies, but reports no new clinical results.
June 2006 in “Journal of the American Academy of Dermatology” Clear glass lets most UV rays through, so it's important to know how well different glasses block UV to protect yourself.
This study found that the hair of a 16th-century female mummy discovered in Paju was remarkably well-preserved due primarily to a calcium-based surface coating that likely inhibited moisture and microorganism infiltration.
This review discusses the clinical forms and causes of androgenization in women, as well as therapeutic options, reporting success with antiandrogens like cyproterone acetate and spironolactone for skin symptoms, though results are not permanent.
In this study, the average force required to pluck hair was significantly lower in malnourished adults, especially those with kwashiorkor, compared to well-nourished individuals.
August 2022 in “International Journal of Dermatology” In this study, low-dose oral minoxidil and sublingual minoxidil were generally well-tolerated in children with alopecia, with mild hypertrichosis as the most common adverse event.
June 2022 in “Plastic and reconstructive surgery. Global open” This study found that platelet-rich plasma treatment significantly improved patients' quality of life and emotional well-being 3-5 months after treatment for hair loss.
June 2007 in “Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii” This article discusses androgenetic alopecia in men and reports that finasteride at 1 mg/day for 24 months is generally well tolerated and may effectively inhibit hair loss.
378 citations
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November 2011 in “Human reproduction update” This review discusses the epidemiology, causes, diagnosis, and management of hirsutism in women, noting that effective treatment requires addressing the root cause as well as the hair growth.
235 citations
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September 2004 in “The Journal of urology/The journal of urology” This review discusses the role of dihydrotestosterone in benign prostatic hyperplasia and reports no new results; the authors highlight 5alpha-reductase inhibitors as a well-established treatment option.
218 citations
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January 2013 in “The Lancet Oncology” This review discusses the pathobiology of chemotherapy-induced alopecia and highlights challenges in managing it, reporting no new clinical results and emphasizing the need for well-designed preclinical models to develop effective treatments.
209 citations
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March 1989 in “Journal of The American Academy of Dermatology” This study found that recombinant human leukocyte interferon alfa-2a achieved a 64% overall antitumor response rate in patients with early and advanced cutaneous T cell lymphoma and was generally well-tolerated.
182 citations
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December 2021 in “Cosmetics” This literature review discusses recent advances in using essential oils and their components in cosmetic products, highlighting their diverse benefits and challenges in formulation due to varying chemical profiles, as well as addressing safety considerations for these natural ingredients.
164 citations
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April 2008 in “Cochrane library” This review of interventions for alopecia areata found no significant treatment benefits for hair growth compared to placebo, indicating a need for larger, well-conducted studies.