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Finasteride exposure harms tadpole reproduction and hormone balance.

A new surgical method using special sutures significantly reduced wound size and prevented disease return in patients with a scarring scalp condition.

CYP2B12 enzyme in skin cells converts arachidonic acid into specific bioactive lipids.

Vitiligo is a skin condition causing white spots, more common in women, often starts before age 20, and can affect mental health.

Testosterone is important for men's sexual function, may help some women's sexual desire, while other hormones and neurotransmitters also play complex roles in sexual behavior.

β-catenin is essential for stem cell activation and proliferation in hair follicles.

Anticancer drugs are increasingly found in surface waters, and their long-term environmental effects are not well understood, requiring better testing methods.

The document concludes that the understanding of scar formation is incomplete and current prevention and treatment for hypertrophic scars and keloids are not fully effective.

Congenital Adrenal Hyperplasia is a genetic disorder with two forms, causing symptoms like early puberty and severe acne, but can be identified through screening and treated with glucocorticoids.

The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.

The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.

Oral retinoids are effective for various skin conditions but have side effects and should not be used during pregnancy.

SHISA6 helps maintain certain stem cells in mouse testes by blocking signals that would otherwise cause them to differentiate.

Vervet monkeys show physical changes like hair loss and scrotal color changes due to stress or nutrition issues.

Certain fungi and bacteria help orchid seeds germinate and plants grow better.

Fadrozole and finasteride change gene expression related to sex hormones and thyroid hormones in frog larvae development.

WNT10A helps esophageal cancer cells spread and keep renewing themselves.

Tcf3 helps cells move and heal wounds by controlling lipocalin 2.

Impaired androgen production in 46,XY DSDs causes ambiguous genitalia and requires long-term care.

Certain drugs that block specific enzymes can help treat prostate diseases.

The protein StAR is found in 17 different organs and can affect hair loss and brain functions, but its full role is not yet fully understood.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

5-alpha reductase inhibitors slightly increase the risk of sexual and mood side effects, and breast growth in men.

Proper control of β-catenin activity is crucial for development and preventing diseases like cancer.

The Brazilian Society of Dermatology agrees that oral isotretinoin is effective for acne and other skin conditions, and it's safe when monitored, but more research is needed on dosing and duration.

New physical methods like electrical currents, ultrasound, and microneedles show promise for improving drug delivery through the skin.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

The genes OVOL1 and OVOL2 are important for hair growth and may be involved in a type of skin tumor.

The Mason gastric bypass is a better surgery for weight loss with fewer complications compared to other methods.

Mesenchymal stem cell therapy may help treat alopecia areata by promoting hair growth and reducing inflammation.