May 2026 in “Malaysian Journal of Medicine and Health Sciences” This study found that in a testosterone-induced androgenetic alopecia mouse model, the combination of PRP-derived small extracellular vesicles and 5% minoxidil significantly improved hair follicle density and the anagen-to-telogen ratio compared to minoxidil alone, suggesting a synergistic effect that enhances hair growth.
October 2018 in “Clinical approaches and procedures in cosmetic dermatology” This source reviews the use of hyaluronic acid fillers for lip augmentation and correction, highlighting their safety and effectiveness, while noting potential adverse effects and the importance of managing complications.
February 2025 in “International Journal of Dermatology” In this review, researchers examined pressure alopecia related to injectable treatments, identifying that injected volume can compress blood vessels, leading to hair loss through ischemia and inflammation, which emphasizes the need for targeted risk management and therapeutic strategies in dermatology.
51 citations
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May 2010 in “Journal of Drug Targeting” This study found that Transcutol-containing vesicles improved the delivery of minoxidil to deeper skin layers in vitro but did not facilitate its permeation through the skin.
1 citations
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July 2023 in “International Journal of Biological Macromolecules” In this study, researchers developed a composite paste system using minoxidil-loaded nanoparticles and valproic acid, enhanced by roller-microneedles, which significantly stimulated hair regeneration and perifollicular vascularization in an androgenetic alopecia mouse model, reducing side effects compared to traditional treatments.
11 citations
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May 1998 in “Hair transplant forum international” This article reviews debates over hair restoration density relative to graft techniques, focusing on arguments for and against using large grafts for better density, and reports no new data.
June 2026 in “Vestnik dermatologii i venerologii” This study evaluated the use of Jet Peel technology, a non-invasive hydroporation method, in treating androgenetic and telogen effluvium alopecia, finding improvements in hair growth and thickness, and a reduction in associated scalp conditions.
3 citations
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December 2020 in “Journal of Cosmetic Dermatology” This study reported that autologous whole fat injection in the scalp considerably increased hair growth in patients with androgenetic alopecia.
March 2023 in “JIIS (Jurnal Ilmiah Ibnu Sina): ilmu farmasi dan kesehatan” This study concluded that the optimum biotin microemulsion hair tonic composition involves span 80 (20%), tween 80 (9.47%), and PEG 400 (5%), providing favorable viscosity and globule size.
10 citations
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May 2021 in “Expert Opinion on Drug Delivery” This study found that CoQ10 formulated in transethosomes showed improved penetration and a better clinical response in treating androgenic alopecia compared to CoQ10 solution.
March 2013 in “Revista Brasileira de Cirurgia Plástica” This article reviews advances in hair transplant techniques such as megasessions of micro and mini grafts, highlighting platelet growth factors' potential to enhance hair density, without reporting new clinical findings.
January 2019 in “Journal of clinical and cosmetic dermatology” This article discusses the potential of combining growth factor therapy with LLLT LED therapy for hair regrowth in androgenetic alopecia, but it does not report new clinical results.
1 citations
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January 1996 in “Aesthetic Plastic Surgery” This study suggests that the tumescent technique can improve hair micrografting by effectively providing anesthesia and reducing bleeding without the need for multiple needle injections or nerve blocks.
July 2017 in “DOAJ (DOAJ: Directory of Open Access Journals)” In this patient series, researchers observed that subcutaneous scalp injections of adipose tissue enriched with stem cells showed potential as a safe and promising treatment for early genetic hair loss in men and women, based on photographic and quantitative assessments.
April 2017 in “Journal of Investigative Dermatology” This study found that lymphatic vessels promote hair follicle growth in mice, suggesting new therapeutic strategies for hair loss treatments.
This study demonstrated that the IVL-DrugFluidic® platform is effective for mass-producing finasteride-loaded polymeric microspheres for long-acting injectables, maintaining stable drug release without an initial burst for a month.
March 2022 in “Al-Azhar International Medical Journal (Print)” In this study, among individuals with androgenic alopecia, stromal vascular fraction injections led to greater clinical improvement and hair density increases compared to nanofat injections, with 26.7% of participants showing great improvement versus 6.7% in the nanofat group after six months.
3 citations
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January 2021 in “Hair transplant forum international” This study found that visual hair density is better correlated with hair count and shaft diameter, leading to the development of the Hair Diameter Index used in planning hair restoration procedures.
13 citations
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August 2016 in “Journal of Cosmetic Dermatology” This study found that intradermal injection of normal saline before follicular unit extraction significantly reduced wound size and skin mass removed compared to acute extraction, suggesting it minimizes skin injury in this procedure.
January 2017 in “Archives of Aesthetic Plastic Surgery” This study reported that using a shampoo and tonic containing horse placental growth factor improved hair thickness and density in postpartum women over three months.
2 citations
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April 2017 in “Plastic and Aesthetic Nursing” This discussion reviews the trend towards nonsurgical hair loss treatments, emphasizing that options like platelet-rich plasma therapy are increasingly used despite not being covered by Canadian health insurance; it presents no clinical findings.
23 citations
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June 1993 in “PubMed” This study found that a vitamin B-group and L-cystine combination therapy improved hair quality and growth in women with diffuse effluvia, with one formulation showing greater efficacy than another and both performing better than placebo.
4 citations
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May 2023 in “JAAD case reports” This study highlights the significant risk of vascular embolism associated with hyaluronic acid filler injections, emphasizing concerns about potential irreversible damage when fillers are injected in "unexplored" facial areas due to complex and variable facial anatomy.
September 2017 in “Springer eBooks” PRP injection therapy shows promise for treating hair loss, increasing hair count and thickness with minimal side effects.
May 2021 in “F1000Research” This study describes a case series where combining PRP and stromal vascular fraction cells for androgenic alopecia led to denser hair growth and improved hair quality in three patients.
January 2005 in “Chinese Journal of Medical Aesthetics and Cosmetology” This study found that hair autotransplantation, with techniques such as keeping fat around hair follicles and sheath-insert transplantation, can result in a natural appearance and 33% higher density compared to traditional methods.
2 citations
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April 2014 in “International Wound Journal” The authors reported that V-Y-S plasty was a safe one-stage method for reconstructing very large scalp alopecia following burns or surgeries.
This review of SVF treatment for androgenetic alopecia found a significant increase in hair density across studies with no serious adverse events, but calls for standardized protocols and further research.
December 2019 in “Journal of Cosmetic Dermatology” In this study, researchers developed an innovative training model using oranges to practice designing the scalp's parietal whorl for hair transplantation. They reported that a density of 40-50 follicular units per cm² achieved better results, aiding surgeons in improving their technique.