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Genetics, nutrition, lifestyle, and hormones affect early grey hair, but more research is needed.

Intravenous calcium therapy is a safe and effective treatment for a rare type of rickets.

Methotrexate and vitamin D3 are potentially more effective and safer than triamcinolone for treating localized alopecia areata.

Vitamin C helps adipose-derived stem cells grow and may support hair growth.

An enzyme other than TNAP might be responsible for vitamin B-6 metabolism in the skin.

A 3-year-old with vitamin D-resistant rickets and severe hair loss died despite treatment, highlighting the need for improved management of the condition.

Eating too much or too little vitamin A can cause hair loss.

Certain groups may need vitamin supplements to improve hair health and prevent other health problems.

High-dose vitamin A and E with zinc improved blood sugar control and insulin function in diabetics, but may cause hair loss.

High prolactin levels might be linked to hair loss in autoimmune thyroid disease, but more research is needed.

Lower SHBG levels may increase the risk of PCOS.

Vitamin B6 helps increase hair growth and density in rabbits by affecting certain cell signaling pathways.

Vitamin E affects liver metabolism, enhancing stress resistance, reducing blood clotting, and altering hormone processing.

Some breast cancer patients on hormone therapy experience hair loss, and treatments like certain topical inhibitors and supplements may help without harming their cancer prognosis.

Japanese patients with alopecia areata often have a higher BMI and consume more vitamin C, fruit, and retinol, which may affect their condition's development or severity.

Retinoids are effective for acne but can cause serious side effects.

The European Society of Endocrinology advises individualized long-term management for PCOS, focusing on lifestyle changes, accurate diagnosis, and treatments for associated health risks and symptoms.

Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

People with myotonic dystrophy type 1 have a higher chance of getting skin tumors, including melanoma.

Statins may help treat PCOS by lowering androgen levels and improving cholesterol.

Finasteride effectively reduces hair growth in women with polycystic ovary syndrome or idiopathic hirsutism.

The Rotterdam Study found risk factors for elderly diseases, links between lifestyle and genetics with health conditions, and aimed to explore new areas like DNA methylation and sensory input effects on brain function.

Significant progress was made in understanding PXE, but effective treatments are still needed.

Aging causes hair loss and graying due to stem cell decline and changes in cell behavior and communication.

Vitamins A, B, C, and D are important for skin health and are being explored for new uses, but more research is needed to confirm their effectiveness.

The document concludes that biotin, folate, and RGD peptides are promising for targeting cancer cells with prodrugs, but the conjugates are not yet tested for use.

Retinoic acid helps activate hair growth in people with common hair loss by working on a specific cell growth pathway.

New treatments are needed for PCOS that target its genetic, hormonal, and metabolic causes.

Tiger cubs fed artificial milk lacking certain amino acids developed eye problems and hair loss.

Using stem cells from hair follicles to treat female hair loss is safe and effective after six months.