181 citations,
February 2019 in “Cell” Innate lymphoid cells help control skin bacteria by regulating sebaceous glands.
53 citations,
April 2016 in “Stem cell research & therapy” LL-37 helps stem cells grow and move, aiding tissue regeneration and hair growth.
40 citations,
September 2007 in “Bone marrow transplantation” Certain chemotherapy drugs can cause permanent hair loss in stem cell transplant patients.
29 citations,
February 2011 in “PloS one” Astressin-B can reverse and prevent hair loss in stressed mice.
28 citations,
June 2021 in “Frontiers in immunology” A protein called lfTSLP is important in causing allergic and other skin diseases and could be a target for treatment.
11 citations,
August 2021 in “Aging” Collagen and TGF-β2 help maintain hair cell shape and youthfulness.
10 citations,
July 1994 in “Journal of Dermatological Science” Cyclosporin extends hair growth in mice, but high-dose corticosteroids block this effect.
9 citations,
June 2023 in “Cells” Certain natural and synthetic compounds may help treat inflammatory skin diseases by targeting a specific signaling pathway.
6 citations,
June 2023 in “American Society of Clinical Oncology Educational Book” Cannabis, cryotherapy, and scalp cooling can help improve the quality of life for chemotherapy patients.
1 citations,
January 2017 in “Current Dermatology Reports” Early baldness in men may indicate risks for obesity, metabolic syndrome, insulin resistance, and heart disease, similar to women with PCOS. Alopecia areata is often linked with autoimmune diseases and mental health issues. Certain hair disorders are due to genetic issues, and chemotherapy can cause hair loss through specific biological pathways. Iron deficiency's link to hair loss is still disputed.
January 2022 in “Clinical Cases in Dermatology” Some hair loss from medication may reverse after stopping the drug, but treatment options are limited and ongoing research is needed.
14 citations,
January 2008 in “Dermatology” Vitamin D made by the skin plays a role in immune defense and skin health, and more research is needed to understand its full effects.
9 citations,
January 2005 in “Experimental dermatology” Melatonin receptors in hair follicles help regulate hair growth and could treat hair loss.
76 citations,
January 2007 in “American Journal of Clinical Dermatology” Women with PCOS often have skin problems like excessive hair, acne, hair loss, and dark patches, which can be treated with hormonal and non-hormonal therapies.
51 citations,
January 2012 in “Annals of dermatology/Annals of Dermatology” A boy with alopecia regrew hair using a vitamin D cream after other treatments failed.
48 citations,
January 2015 in “Indian Journal of Dermatology, Venereology and Leprology” Vitamin D is important for skin health and can help treat psoriasis, atopic dermatitis, and vitiligo.
14 citations,
January 2019 in “PubMed” Vitamin D might be involved in the development of alopecia areata and could help in its treatment.
51 citations,
September 2008 in “Journal of Investigative Dermatology” Vitamin D receptor may help protect against UV-induced skin cancer.
158 citations,
August 2011 in “Reviews in endocrine and metabolic disorders” Vitamin D and its receptor regulate skin functions like cell growth, immunity, hair cycle, and tumor prevention.
22 citations,
November 2016 in “International journal of molecular sciences” Vitamin D receptor is important for regulating hair growth and wound healing in mice.
28 citations,
August 2011 in “Journal of The American Academy of Dermatology” Early hair loss may indicate prostate issues.
42 citations,
August 1999 in “The American journal of pathology” Basal cell carcinomas have much higher levels of Vitamin D3 receptors compared to healthy skin.
3 citations,
November 2021 in “World Journal of Clinical Pediatrics” Vitamin D might help treat some types of hair loss, but more research is needed.
23 citations,
April 1996 in “PubMed” Vitamin D3 and parathyroid hormone-related peptide may have important uses in skin treatments.
20 citations,
May 2007 in “JDDG Journal der Deutschen Dermatologischen Gesellschaft” Etanercept effectively treated a severe skin condition when other treatments failed.
6 citations,
August 1989 in “European journal of pediatrics” Child with rickets improved with a specific vitamin D therapy, but alopecia did not change.
4 citations,
May 2021 in “Molecules” The hair test for vitamin D could be a useful alternative to blood tests, providing a longer-term vitamin D status, but more research is needed.
50 citations,
October 1986 in “European journal of pediatrics” A boy with severe Vitamin D-resistant rickets did not respond to treatment and lacked a common symptom, suggesting a need for alternative treatments.
11 citations,
March 2015 in “Life sciences” Vitamin D3-activated cell byproduct promotes hair growth in mice by increasing blood vessel growth.
36 citations,
February 2007 in “Journal of biological chemistry/The Journal of biological chemistry” The vitamin D receptor can work without its usual activating molecule.