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      COVID-19 and Sex Differences: Mechanisms and Biomarkers

      research COVID-19 and Sex Differences

      185 citations , August 2020 in “Mayo Clinic Proceedings”
      This review discusses biological sex differences in COVID-19 outcomes and reports no new clinical results; it identifies a need for studies to clarify how sex influences disease progression.
      A Hot New Twist to Hair Biology: The Role of TRPV1 in Human Hair Growth Control

      research A Hot New Twist to Hair Biology

      174 citations , April 2005 in “˜The œAmerican journal of pathology (Print)”
      This study found that TRPV1 activation in human scalp hair follicles inhibited hair shaft elongation, suppressed proliferation, and induced apoptosis, suggesting TRPV1 as a potential target for managing hair growth and epithelial disorders.
      Cutaneous Complications of Chemotherapeutic Agents

      research Cutaneous complications of chemotherapeutic agents

      172 citations , November 1983 in “Journal of The American Academy of Dermatology”
      This article discusses the cutaneous side effects of various chemotherapeutic agents but reports no new clinical results; the authors emphasize the importance of dermatologists recognizing drug-induced skin reactions to better patient care.
      The Hair Follicle as an Estrogen Target and Source

      research The Hair Follicle as an Estrogen Target and Source

      159 citations , July 2006 in “Endocrine Reviews”
      This article discusses the influence of estrogens on hair follicle growth and metabolism, suggesting a significant role alongside androgens in hair growth control but reports no new clinical results.
      The Pharmacology of Methotrexate

      research The pharmacology of methotrexate

      155 citations , August 1991 in “Journal of The American Academy of Dermatology”
      This article reviews methotrexate's pharmacokinetics and toxicity, emphasizing the role of urinary excretion and leucovorin in avoiding most toxic reactions; it provides no new clinical results.
      Minoxidil Use in Dermatology, Side Effects, and Recent Patents

      research Minoxidil Use in Dermatology, Side Effects and Recent Patents

      152 citations , April 2012 in “Recent Patents on Inflammation & Allergy Drug Discovery”
      This review describes minoxidil's hair regrowth mechanism and discusses dermatological applications, but reports no new clinical results, emphasizing the need for regular use and addressing allergic reactions.
      Drug-Induced Hair Loss and Hair Growth

      research Drug-Induced Hair Loss and Hair Growth

      147 citations , April 1994 in “Drug Safety”
      Some drugs can cause hair loss or increase hair growth, but these effects are usually reversible when the drug is stopped.
      Transfollicular Drug Delivery: Is It a Reality?

      research Transfollicular drug delivery—Is it a reality?

      141 citations , November 2005 in “International journal of pharmaceutics”
      This review examines the role of hair follicles and sebaceous glands in percutaneous drug delivery but does not report new clinical results; it calls for further exploration of follicle-targeting therapies.
      Mechanical and Biological Properties of Keratose Biomaterials

      research Mechanical and biological properties of keratose biomaterials

      140 citations , August 2011 in “Biomaterials”
      This study observed that keratose, derived from human hair, integrated well in mouse tissue and remodeled with collagen, suggesting potential as a non-toxic biomaterial for regenerative applications.
      EEMCO Guidance for the In Vivo Assessment of Skin Greasiness

      research EEMCO Guidance for the in vivo Assessment of Skin Greasiness

      137 citations , January 2000 in “Skin Pharmacology and Physiology”
      This review outlines the factors affecting skin greasiness and sebum production, highlighting measurement challenges but reports no new clinical findings; further research may guide sebosuppressive treatments for acne.
      Finasteride

      research Finasteride

      125 citations , January 1999 in “Drugs”
      This study found that oral finasteride 1 mg/day promotes hair growth and prevents further hair loss in a significant proportion of men with male pattern hair loss over two years.
      Keratin 17 Null Mice Exhibit Age- And Strain-Dependent Alopecia

      research Keratin 17 null mice exhibit age- and strain-dependent alopecia

      122 citations , June 2002 in “Genes & Development”
      This study found that K17 is crucial for the structural integrity and survival of hair-producing cells, with K17 null mice developing alopecia due to hair fragility and follicular alterations.
      Histopathology of Non-Scarring Alopecia

      research Histopathology of non-scarring alopecia

      122 citations , April 1995 in “Journal of Cutaneous Pathology”
      The document describes how to tell different types of non-scarring hair loss apart by looking at hair and scalp tissue under a microscope.
      Effect of Estrogens on Skin Aging and the Potential Role of SERMs

      research Effect of estrogens on skin aging and the potential role of SERMs

      120 citations , October 2007 in “Clinical Interventions in Aging”
      This review discusses the effects of estrogens on skin aging and highlights the potential benefits of estrogen replacement therapy and selective estrogen receptor modulators for improving skin health in postmenopausal women, but reports no new clinical findings.
      Acne: Hormonal Concepts and Therapy

      research Acne: Hormonal concepts and therapy

      118 citations , September 2004 in “Clinics in Dermatology”
      This review discusses the role of hormones in acne vulgaris and highlights the need for further research on their mechanisms of action; it reports no new clinical results.
      Severe Acute Respiratory Syndrome Among Children

      research Severe Acute Respiratory Syndrome Among Children

      115 citations , June 2004 in “Pediatrics”
      This study found that children are susceptible to SARS-CoV, with good short- to medium-term outcomes, and that sore throat and neutrophilia can predict severe illness.
      Targeting the Wnt Pathways for Therapies

      research Targeting the Wnt pathways for therapies

      112 citations , January 2014 in “Molecular and cellular therapies”
      This review summarizes the current understanding of Wnt signaling in relation to its roles in tissue regeneration and cancer progression and discusses recent medical advancements targeting this pathway for therapeutic purposes.