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480-510 / 1000+ resultsresearch A novel derivative of doxorubicin, AD198, inhibits canine transitional cell carcinoma and osteosarcoma cells in vitro
This study found that the DOX derivative AD198 more effectively inhibited cell viability and induced apoptosis in canine cancer cell lines K9TCC and K9OSA compared to DOX in vitro.
research Chronic graft-versus-host disease – the role of dermatological treatment
This article discusses skin lesions in chronic graft-versus-host disease and highlights the importance of coordinated care between haematologists and dermatologists for effective management; it presents no new clinical results.
research Canine cutaneous epitheliotropic T-cell lymphoma with vesiculobullous lesions resembling human bullous mycosis fungoides
This study found that macroscopic vesiculobullous lesions with epidermal devitalization in dogs are part of the clinical spectrum of canine cutaneous epitheliotropic T-cell lymphoma.
research Novel insights into cardiocutaneous syndromes
This thesis found that desmoplakin mutations in cardiocutaneous syndrome are linked to dose-dependent disease severity and identified mechanisms by which KLHL24 mutations cause cardiomyopathy, with rescue experiments successfully preventing this phenotype in patient-derived heart tissues.
research Cell Proteomic Footprinting: Advances in the Quality of Cellular and Cell-Derived Cancer Vaccines
This article reviews cell proteomic footprinting technology and its application in improving the authentication and quality control of cell-based immunotherapeutics, without providing new clinical results.
research Bio‐active designed peptide for hair keratin strengthening
This research reports that KCV and its palmitoylated derivatives show strong effectiveness in strengthening hair proteins, indicating their potential for use in advanced hair care products.
research Role of vascular endothelial growth factor in androgenetic alopecia
Vascular endothelial growth factor might be involved in common hair loss.
research Evaluating the quality of studies reporting on clinical applications of stromal vascular fraction: A systematic review and proposed reporting guidelines (CLINIC-STRA-SVF)
This study proposes a reporting guideline, CLINIC - STRA-SVF, to standardize and improve the design and reporting of clinical studies involving SVF, highlighting its safety and effectiveness despite the low level of current evidence.
research Sometimes Marketing Efforts by Advocacy Organizations Can Lose Touch with the Nuances of Appropriateness
This article discusses the ethical concerns and implications of a partnership between the National Prostate Cancer Coalition and Viadur, including the perceived endorsement of a specific drug.
research Safety and efficacy of low-dose metronomic cyclophosphamide plus vinorelbine in patients with metastatic breast cancer previously treated with anthracyclines and taxanes.
This study observed that a combination of low-dose cyclophosphamide and vinorelbine appears safe and has promising antitumor activity in patients with metastatic breast cancer resistant to anthracyclines and taxanes, achieving a 44% objective response rate at 6 months with manageable toxicity levels.
research Management of Adult Facial Vascular Anomalies
This article reviews the classification and treatments of vascular anomalies, such as hemangiomas and vascular malformations, and reports no new clinical results; it emphasizes the importance of managing patient expectations due to treatment limitations.
research Reviewer #2 (Public Review): CaBP1 and 2 enable sustained CaV1.3 calcium currents and synaptic transmission in inner hair cells
CaBP1 and 2 are necessary for maintaining calcium currents and hearing in inner ear cells.
research VIJAYA-The one who fights to win
This narrative from Vijaya, a breast cancer patient, shares her personal experience with diagnosis, treatment, and support, highlighting the importance of emotional resilience and support groups.
research A Novel Connexin 26 Mutation in a Patient Diagnosed with Keratitis–Ichthyosis–Deafness Syndrome
This study presents evidence that keratitis–ichthyosis–deafness syndrome is caused by a mutation in the connexin 26 gene, expanding the gene's known involvement in various disorders.
research Damage of hair fibers as evaluated by an electrical capacitance technique
research Synthesis of avicequinone c and analogs toward the study of 5α-reductase inhibitory activity
This study found that 2-hydroxy-1,4-naphthoquinone was the most effective inhibitor of steroid 5α-reductase, showing stronger inhibition than avicequinone C in HaCaT cell assays.
research MCMV Infection Lowers the Threshold for the Development of Clinical GvHD after Allogeneic Bone Marrow Transplantation.
This study found that CMV infection in a mouse model of allogeneic transplantation was associated with increased allo-reactive T cell expansion and exacerbated graft-versus-host disease, highlighting the need for effective GvHD prophylaxis and treatment.
research Patchy presentation of central centrifugal cicatricial alopecia
This case report highlights that CCCA can present with multifocal patchy hair loss in younger men of African descent, suggesting the need for careful evaluation when diagnosing atypical alopecia patterns.
research Hair-growth stimulation by conditioned medium from vitamin D3-activated preadipocytes in C57BL/6 mice
This study found that using conditioned medium from vitamin D3 pre-activated preadipocytes enhanced hair regeneration in mice by promoting angiogenesis.
research Woodhouse-Sakati Syndrome: The New Genetic Variant of DCAF17 In 2 Adult Sisters
This report highlights a new genetic variant of Woodhouse-Sakati syndrome in two sisters from the first identified family case in Russia, emphasizing the varied manifestations of the disorder and the importance of genetic testing for diagnosis and patient-specific treatment planning.
research Confluent Verruca Vulgaris Arising Within Bilateral Eyebrow Tattoos
This overview outlines the Dermatologic Surgery journal's comprehensive focus on cosmetic and reconstructive procedures, but it does not present any new research findings.
research Central centrifugal cicatricial alopecia: Past, present, and future
This review discusses the evolution and ongoing debate about the causes of central centrifugal cicatricial alopecia in African American women, without presenting new clinical findings.
research Commentary on Clinical Application of Cultured Stratified Epithelial Sheets Grown Under Feeder or Feeder-Free Conditions for Stable Vitiligo
This journal overview describes the comprehensive content and focus of the Dermatologic Surgery journal, highlighting its role in delivering the latest scientific information for various skin surgery techniques, but it presents no new research findings.
research Human placental mesenchymal stromal cell‐derived exosome‐enriched extracellular vesicles for chronic cutaneous graft‐versus‐host disease: A case report
This case report observed that treatment with human placental mesenchymal stromal cell-derived exosome-enriched extracellular vesicles may improve symptoms of chronic cutaneous graft-versus-host disease, including hyperpigmentation and skin ulcers, in a patient resistant to conventional therapies.
research Vitamin C Deficiency-Induced Pulmonary Arterial Hypertension
This case report observed that pulmonary arterial hypertension in a man with severe vitamin C deficiency resolved after vitamin C supplementation, suggesting a potential role of vitamin C in managing this condition.
research Familial Dyskeratotic Comedones: A Case Report and Literature Review
In this report, a 54-year-old woman with familial dyskeratotic comedones showed slight improvement in skin lesions after topical retinoids and urea cream. This source also describes the first dermoscopic findings for this condition and reviews 21 previous cases.
research Surveillance dan Penyebaran Penyakit Tangan, Kaki, dan Mulut (HFMD)
This article discusses the surveillance and spread of hand, foot, and mouth disease in China, Singapore, and Indonesia, and reports no new results, emphasizing the need for improved prevention and management strategies.
research Comparative Evaluation of Wound Healing Effect of Cord Blood Low Molecular Weight Fraction (Below 5 kDa) and Actovegin Drug in Skin Cryolesions
In this study on rats, CBF injections demonstrated significant wound healing effects and improved recovery after skin cryoablation, similar to the effects observed with Actovegin.
research Clinical Management of Vitamin A Responsive Dermatosis in a Labrador Retriever Dog
This study presented a case of a Labrador Retriever with recurrent skin lesions and confirmed vitamin A-responsive dermatosis after successful treatment with vitamin A therapy, highlighting the importance of considering vitamin A deficiency in primary keratinization disorders.