90 citations
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November 1980 in “Annals of Internal Medicine” This study observed that prolonged minoxidil treatment may improve renal function in some patients with refractory malignant hypertension, whereas the impact was mixed in patients with benign hypertension.
April 2023 in “Medicina Clínica (english Edition)” In this study, a risk score was developed and validated to identify patients at high risk of clinical failure after femoropopliteal peripheral vascular intervention, aiming to guide the selection of patients who may benefit from paclitaxel-coated devices or alternative strategies.
319 citations
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March 2023 in “Science Advances” This study demonstrated that a wearable bioelectronic patch with combined therapy significantly accelerated chronic wound healing in a rodent model by monitoring and treating wounds noninvasively.
8 citations
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October 2022 in “Frontiers in Bioengineering and Biotechnology” This study found that HFV70 cryogels, made from Flammulina velutipes extract and hydroxyethyl cellulose, effectively promoted rapid hemostasis and tissue regeneration in full-thickness skin defects in rats, demonstrating improved hemocompatibility, cytocompatibility, antimicrobial, and antioxidant properties.
35 citations
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March 2005 in “Journal of Investigative Dermatology” In this in vitro study, minoxidil, diazoxide, and the novel compound NNC 55-0118 increased hair follicle growth, supporting deer follicles as a viable bioassay for ATP-sensitive potassium channel modulators.
February 2025 in “Journal of the American Academy of Dermatology” Spironolactone helps prevent swelling caused by minoxidil in women with hair loss.
91 citations
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July 2010 in “Tissue Engineering Part A” This study found that low oxygen conditions and ECM degradation products increased the proliferation and migration of perivascular stem cells without altering their phenotype, suggesting potential roles in tissue repair.
1 citations
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November 2005 in “Dermatologic Surgery” This study found that aminoguanidine induces VEGF mRNA expression in stored hair follicle micrografts and outer root sheath cells, suggesting potential for enhancing growth factor production during storage.
48 citations
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January 2020 in “Cochrane Database of Systematic Reviews” This study found that serlopitant may reduce pruritus intensity compared to placebo in patients with chronic pruritus of unknown origin, though evidence is of low certainty and effects on other outcomes are unclear.
July 2020 in “Hair transplant forum international” This case report describes how nitroglycerin (sublingual) was used to prevent further scalp necrosis during hair restoration surgery, particularly in a patient experiencing early necrosis linked to local anesthetics with epinephrine.
July 2026 in “Journal of the American Academy of Dermatology”
December 2025 in “Cell Communication and Signaling” This study discovered that minoxidil affects hematopoiesis by downregulating wnt4, leading to suppression of hematopoietic stem and progenitor cells and alleviating MDS-like symptoms in zebrafish and mice, with hematologic safety achieved at optimized doses.
24 citations
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November 2023 in “Regenerative Biomaterials” In this review, the authors summarized the potential therapeutic effects of metal ions in treating cardiovascular diseases, highlighting their roles in protecting cells, inducing angiogenesis, and adjusting ion channel functions, as well as discussing delivery strategies involving biomaterials.
May 2024 in “Regenerative Therapy” This laboratory study found that dendrobium officinale polysaccharide (DOP) stimulated hair follicle and hair growth in mice by activating the WNT signaling pathway.
July 2026 in “The Bioscan.” This review details the process and advantages of drug repurposing, highlighting its potential as a cost-effective and expedited alternative to traditional drug development while summarizing various strategies and successful examples, and exploring related regulatory challenges.
20 citations
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August 2008 in “Journal of Medical Case Reports” This case report describes a probable hypersensitivity reaction to a single intravenous dose of ondansetron, highlighting the need for cautious use, especially in outpatient settings.
July 2024 in “Bozok Tıp Dergisi” This study found that using a new method to apply platelet-rich plasma during surgery improved early outcomes for patients with hip avascular necrosis, including those with a history of Covid-19.
15 citations
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August 1989 in “Archives of Dermatology” This article hypothesizes that minoxidil may act as an endothelium-derived relaxing factor agonist, which could explain both its vasodilatory properties and its potential effect on hair growth; however, it reports no new experimental results.
March 2025 in “Journal of the American Academy of Dermatology” Low-dose oral minoxidil doesn't affect blood pressure in patients taking blood pressure meds.
1 citations
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December 2025 in “Baylor University Medical Center Proceedings” Leuprolide may better manage cholesterol and blood pressure in PCOS than spironolactone.
May 2026 in “The Bioscan.” This review discusses the process and advantages of drug repurposing, highlighting its potential to expedite development and improve therapeutic outcomes with examples like sildenafil and metformin.
15 citations
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July 1991 in “International Journal of Dermatology” This article discusses the technique of laser Doppler velocimetry for measuring cutaneous blood flow and does not report new research findings.
28 citations
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November 2009 in “European Journal of Neuroscience” This study found that progesterone can increase glycine release in rat brainstem neurons through its conversion to allopregnanolone, which modulates presynaptic GABA receptor activity.
1 citations
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August 1989 in “Archives of Dermatology” This article reviews recent discoveries about the role of the nitroxide free radical NO in vascular physiology and suggests potential implications for minoxidil's vasodilatory action, but reports no new clinical findings.
October 2023 in “Journal of The American Academy of Dermatology” This article discusses the use of low-dose oral minoxidil as an off-label treatment for androgenetic alopecia but reports no new clinical results.
This study found that a mitoxantrone, vincristine, and prednisolone regimen effectively treated recurrent breast cancer with a 70% response rate, though it was associated with significant myelosuppression.
This study found that activation of delta-opioid receptors in keratinocytes may delay the expression of the PER2 gene, suggesting a possible link to cancer development through circadian rhythm disruption.
6 citations
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May 2023 in “Molecules” In this study, dry powder inhalers containing Cepharanthine were administered to rats with acute lung injury, significantly reducing pulmonary edema, hemorrhage, and inflammatory markers, suggesting its potential as an effective anti-inflammatory treatment when inhaled directly into the lungs.
May 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study found that topical minoxidil is potentially the safest hair loss treatment for dialysis patients, while caution is advised for oral treatments like low-dose minoxidil due to possible systemic side effects.
32 citations
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December 2017 in “Journal of Drug Delivery Science and Technology” This study found that co-delivery of minoxidil and caffeine in transfersomes with an optimized polysorbate formulation enhanced hair length and weight in vivo.